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The Meselson-Stahl Experiment (1957–1958), by Matthew Meselson and Franklin Stahl
By: Victoria Hernandez
| Published: Apr 18, 2017
In an experiment later named for them, Matthew Stanley Meselson and Franklin William Stahl in the US demonstrated during the 1950s the semi-…
DNA ReplicationMeselson, MatthewStahl, Franklin W.DNA--SynthesisDNA
Jennifer Doudna and Emmanuelle Charpentier’s Experiment About the CRISPR/cas 9 System’s Role in Adaptive Bacterial Immunity (2012)
By: Meilin Zhu
| Published: Oct 19, 2017
In 2012, Jennifer Doudna, Emmanuelle Charpentier from the University of California, Berkeley, in Berkeley, California, and Umeå University in Umeå,…
gene editingStreptococcus pyogenesTranscription Activator-Like Effector NucleasesscFV green fluorescent protein, recombinantClustered Regularly Interspaced Short Palindromic Repeats
"Presence of Fetal DNA in Maternal Plasma and Serum" (1997), by Dennis Lo, et al.
By: Cassidy Possehl
| Published: Mar 07, 2017
In the late 1990s researchers Yuk Ming Dennis Lo and his colleagues isolated fetal DNA extracted from pregnant woman’s blood. The technique enabled…
AmniocentesisChorionic Villus SamplingFetusObstetricsDNA
The Hershey-Chase Experiments (1952), by Alfred Hershey and Martha Chase
By: Victoria Hernandez
| Published: Jun 23, 2019
In 1951 and 1952, Alfred Hershey and Martha Chase conducted a series of experiments at the Carnegie Institute of Washington in Cold Spring Harbor,…
BacteriophagesDNACold Spring Harbor LaboratoryProtein PrecursorsAmino Acid Sequence
Harald zur Hausen's Experiments on Human Papillomavirus Causing Cervical Cancer (1976–1987)
By: Grace Kim
| Published: Mar 09, 2017
From 1977 to 1987, Harald zur Hausen led a team of researchers across several institutions in Germany to investigate whether the human papillomavirus…
PapillomavirusesHuman Papilloma VirusHerpes simplex virusCervix uteri--CancerCervical Cancer
CRISPR Acquired Resistance Against Viruses (2007)
By: Meilin Zhu
| Published: Nov 15, 2017
In 2007, Philippe Horvath and his colleagues explained how bacteria protect themselves against viruses at Danisco, a Danish food company, in Dangé-…
gene editingStreptococcus thermophilusvirusesBacteriaRNA
Using Digital PCR to Detect Fetal Chromosomal Aneuploidy in Maternal Blood (2007)
By: Meilin Zhu
| Published: Nov 08, 2017
In 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidy
Shoukhrat Mitalipov and Masahito Tachibana’s Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells (2009)
By: Giselle Lee
| Published: Jan 10, 2018
Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial Diseases
Elizabeth Blackburn, Carol Greider and Jack Szostak's Telomere and Telomerase Experiments (1982-1989)
By: Zane Bartlett
| Published: Mar 24, 2015
Experiments conducted by Elizabeth Blackburn, Carol Greider, and Jack Szostak from 1982 to 1989 provided theories of how the ends of chromosomes,…
TelomereGreider, Carol W.Chromosome replicationTelomeraseDNA
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems