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“Human Organoids: Tools for Understanding Biology and Treating Diseases” (2020), by Frans Schutgens and Hans Clevers
By: Aida Movahed
| Published: Aug 08, 2025
In 2020, Frans Schutgens and Hans Clevers published “Human Organoids: Tools for Understanding Biology and Treating Diseases,” hereafter “Human…
OrganoidsCell Culture Techniques, Three DimensionalPrimary Cell Cultureinduced pluripotent stem cellsAdult Stem Cells
Cerebral Organoid as a Model System in the Study of Microcephaly
By: Dasia Garcia
| Published: May 12, 2017
Scientists use cerebral organoids, which are artificially produced miniature organs that represent embryonic or fetal brains and have many properties…
TechnologyMicrocephalyBrainNeuronsBrain--Diseases--Animal models
"Formation of Genetically Mosaic Mouse Embryos and Early Development of Lethal (t12/t12)-Normal Mosaics" (1964), by Beatrice Mintz
By: Adam R. Navis
| Published: Jan 13, 2009
The paper "Formation of Genetically Mosaic Mouse Embryos and Early Development of Lethal (t12/t12)-Normal Mosaics," by Beatrice Mintz, describes a…
Mintz, BeatriceExperimentsMice
Hanging Drop Tissue Culture
By: Adam R. Navis
| Published: Nov 08, 2007
The hanging drop tissue culture is a technique utilized in embryology and other fields to allow growth that would otherwise be restricted by the flat…
TechnologyTissue cultureTissue Culture Techniques
Telomerase in Human Development
By: Zane Bartlett
| Published: Mar 23, 2015
Telomerase is an enzyme that regulates the lengths of telomeres in the cells of many organisms, and in humans it begins to function int the early…
TelomeraseTelomereDNAMolecular BiologySomatic embryogenesis
The Jackson Laboratory
By: Christina Raup
| Published: Jul 01, 2010
The Roscoe B. Jackson Laboratory, known commonly in the scientific field as the Jackson Laboratory, was founded by Clarence Cook Little in May 1929.…
OrganizationOrganizationsLaboratoriesMiceGenetics
“Part-Human Chimeras: Worrying the Facts, Probing the Ethics” (2007), by Françoise Baylis and Jason Scott Robert
By: Alexis Darby
| Published: Jun 19, 2021
In 2007, Françoise Baylis and Jason Scott Robert published “Part-Human Chimeras: Worrying the Facts, Probing the Ethics” in The American Journal of…
LiteratureChimerismNeuronsChimeraGenetics
Nuclear Transplantation
By: Sean Cohmer
| Published: Jun 14, 2011
Nuclear transplantation is a method in which the nucleus of a donor cell is relocated to a target cell that has had its nucleus removed (enucleated…
Cell nuclei--TransplantationNuclear Transplantation
Francis Sellers Collins (1950- )
By: Tito Carvalho
| Published: Apr 10, 2014
Francis Sellers Collins helped lead the International Human Genome Sequencing Consortium, which helped describe the DNA sequence of the human genome…
Human Genome ProjectNucleotide sequenceSequence Analysis, DNAGenome
Alexis Carrel's Tissue Culture Techniques
By: Lijing Jiang
| Published: Jun 18, 2010
Alexis Carrel, the prominent French surgeon, biologist, and 1912 Nobel Prize laureate for Physiology or Medicine, was one of the pioneers in…
TechnologyCarrel, Alexis, 1873-1944Tissue Culture TechniquesTissue culture