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In 2009, Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers developed the technology of mitochondrial gene replacement therapy to…
TechnologymonkeysGurdon, J. B. (John Bertrand)Briggs, Robert, -1983King, Thomas J. (Thomas Joseph), 1921-2000The San Diego Zoo Institute for Conservation Research (SDZICR) in San Diego, California, is a research organization that works to generate, use, and…
OrganizationpreservationGeneticsEndangered SpeciesDNAAt the turn of the twentieth century, William Bateson studied organismal variation and heredity of traits within the framework of evolutionary theory…
GeneticsHeredityMendel, Gregor, 1822-1884EvolutionEmbryologyCalvin Blackman Bridges studied chromosomes and heredity in the US throughout the early twentieth century. Bridges performed research with Thomas…
DrosophilaHeredityInheritance of acquired charactersColumbia University--Graduate studentsMutationCharles Robert Cantor helped sequence the human genome, and he developed methods to non-invasively determine the genes in human fetuses. Cantor…
Human Genome ProjectDNAfetal developmentFetusEmbryosJohn D. Gearhart is a renowned American developmental geneticist best known for leading the Johns Hopkins University research team that first…
PeopleStem CellsGeneticsBiographyThe paper "Formation of Genetically Mosaic Mouse Embryos and Early Development of Lethal (t12/t12)-Normal Mosaics," by Beatrice Mintz, describes a…
Mintz, BeatriceExperimentsMiceMeiosis, the process by which sexually-reproducing organisms generate gametes (sex cells), is an essential precondition for the normal formation of…
MeiosisReproductionHuman DevelopmentIn 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidyShoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial Diseases