In 2004, Amanda J. Drake and Brian R. Walker published “The Intergenerational Effects of Fetal Programming: Non-genomic Mechanisms for the Inheritance of Low Birth Weight and Cardiovascular Risk,” hereafter, “The Intergenerational Effects,” in the Journal of Endocrinology. In their article, the authors assert that cardiovascular disease may develop via fetal programming, which is when a certain event occurring during a critical point of pregnancy affects the fetus long after birth. Drake and Walker were among the first to show that the programming effects of cardiovascular disease could be sustained across generations through non-genetic means. In “The Intergenerational Effects,” the authors identify how non-genetic mechanisms may perpetuate fetal programming influences over generations, highlighting the importance for further research on fetal programming.

A vasectomy is a surgery that works to inhibit reproduction by interrupting the passage of sperm through the vas deferens, a tube in the male reproductive system. The procedure is a method of inhibiting an individual’s ability to cause pregnancy through sexual intercourse without altering the other functions of the penis and testes. In the US, into the early 1900s, proponents of eugenics, the belief that human populations can be made better by selecting for so-called desirable traits, used the procedure to forcibly sterilize people whom they deemed undesirable. Despite its early associations with eugenics, physicians’ use of vasectomy eventually transitioned into an option for elective contraception. Even with the various shifts in motivation for performing vasectomies, as of 2023, patients have the choice to undergo a sterilization procedure if they want to restrict their own ability to have children.