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“Studies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types: Induction of Transformation by a Desoxyribonucleic Acid Fraction Isolated from Pneumococcus Type III” (1944) by Oswald Avery, Colin MacLeod and Maclyn McCarty
By: Victoria Hernandez
| Published: Jul 08, 2019
In 1944, Oswald Avery, Colin MacLeod, and Maclyn McCarty published an article in which they concluded that genes, or molecules that dictate how…
LiteratureTransformation, BacterialBacterial TransformationStreptococcus pneumoniaeBacterial genetics
The Case of Lydia Fairchild and Her Chimerism (2002)
By: Alexis Darby
| Published: Jun 01, 2021
In 2002, after applying for government assistance in the state of Washington, Lydia Fairchild was told that her two children were not a genetic match…
ChimerismHuman GeneticsForensic geneticsLone twinsPaternity testing
CRISPR Acquired Resistance Against Viruses (2007)
By: Meilin Zhu
| Published: Nov 15, 2017
In 2007, Philippe Horvath and his colleagues explained how bacteria protect themselves against viruses at Danisco, a Danish food company, in Dangé-…
gene editingStreptococcus thermophilusvirusesBacteriaRNA
Using Digital PCR to Detect Fetal Chromosomal Aneuploidy in Maternal Blood (2007)
By: Meilin Zhu
| Published: Nov 08, 2017
In 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidy
Dennis Lo (1963- )
By: Alexis Abboud
| Published: Nov 04, 2014
Dennis Lo, also called Yuk Ming Dennis Lo, is a professor at the Chinese University of Hong Kong in Hong Kong, China. In 1997, Lo discovered fetal…
genetic testingHuman chromosome abnormalities--DiagnosisPrenatal DiagnosisAmniocentesisChorionic Villus Sampling
Shoukhrat Mitalipov and Masahito Tachibana’s Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells (2009)
By: Giselle Lee
| Published: Jan 10, 2018
Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial Diseases
William Thomas Astbury (1898–1961)
By: Victoria Hernandez
| Published: Jun 03, 2019
William Thomas Astbury studied the structures of fibrous materials, including fabrics, proteins, and deoxyribonucleic acid, or DNA, in England during…
DNAX-Ray CrystallographyX-ray crystallography--TechniqueNucleic AcidsDNA-protein interactions
Matthew Stanley Meselson (1930– )
By: Victoria Hernandez
| Published: May 23, 2017
Matthew Stanley Meselson conducted DNA and RNA research in the US during the twentieth and twenty-first centuries. He also influenced US policy…
Holmes, Frederic LawrenceMeselson, MatthewStahl, Franklin W.Watson, James D., 1928-Crick, Francis, 1916-2004
Elizabeth Blackburn, Carol Greider and Jack Szostak's Telomere and Telomerase Experiments (1982-1989)
By: Zane Bartlett
| Published: Mar 24, 2015
Experiments conducted by Elizabeth Blackburn, Carol Greider, and Jack Szostak from 1982 to 1989 provided theories of how the ends of chromosomes,…
TelomereGreider, Carol W.Chromosome replicationTelomeraseDNA
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems