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In 1956, Gunther Stent, a scientist at the University of California Berkeley in Berkeley, California, coined the terms conservative, semi-…
DNADNA ReplicationDNA HelicasesGenesHeredityBetween 1953 and 1957, before the Meselson-Stahl experiment verified semi-conservative replication of DNA, scientists debated how DNA replicated. In…
ChromosomesCalifornia Institute of TechnologyCold Spring Harbor LaboratoryDNA ReplicationIn an experiment later named for them, Matthew Stanley Meselson and Franklin William Stahl in the US demonstrated during the 1950s the semi-…
DNA ReplicationMeselson, MatthewStahl, Franklin W.DNA--SynthesisDNAIn 1954 Max Delbruck published On the Replication of Desoxyribonucleic Acid (DNA) to question the semi-conservative DNA replication mechanism…
LiteratureHolmes, Frederic LawrenceMeselson, MatthewStahl, Franklin W.Watson, James D., 1928-In May 1953, scientists James Watson and Francis Crick wrote the article “Genetical Implications of the Structure of Deoxyribonucleic Acid,”…
LiteratureDNANucleic AcidsDeoxyriboseGeneticsOn 6 May 1952, at King’s College London in London, England, Rosalind Franklin photographed her fifty-first X-ray diffraction pattern of…
LiteratureDNADNA HelicasesX Ray CrystallographyCrystallography, X-RayIn 2001, Yale University Press published Frederic Lawrence Holmes' book, Meselson, Stahl, and the Replication of DNA: A History of "The Most…
LiteratureWatson, James D., 1928-Crick, Francis, 1916-2004Marine Biological Laboratory (Woods Hole, Mass.)DNA ReplicationIn April 1953, Rosalind Franklin and Raymond Gosling, published “Molecular Configuration in Sodium Thymonucleate,” in the scientific journal Nature.…
LiteratureDNADNA HelicasesX Ray CrystallographyMolecular structureIn 2012, Jennifer Doudna, Emmanuelle Charpentier from the University of California, Berkeley, in Berkeley, California, and Umeå University in Umeå,…
gene editingStreptococcus pyogenesTranscription Activator-Like Effector NucleasesscFV green fluorescent protein, recombinantClustered Regularly Interspaced Short Palindromic RepeatsIn the late 1990s researchers Yuk Ming Dennis Lo and his colleagues isolated fetal DNA extracted from pregnant woman’s blood. The technique enabled…
AmniocentesisChorionic Villus SamplingFetusObstetricsDNA