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Roy John Britten (1919-2012)
By: Abhinav Mishra
| Published: Oct 24, 2014
Roy John Britten studied DNA sequences in the US in the second half of the twentieth century, and he helped discover repetitive elements in DNA…
DNAGenomesCalifornia Institute of TechnologyGenetic regulationMice
"Gene Regulation for Higher Cells: A Theory" (1969), by Roy J. Britten and Eric H. Davidson
By: Justin Wolter
| Published: Sep 10, 2013
In 1969, Roy J. Britten and Eric H. Davidson published Gene Regulation for Higher Cells: A Theory, in Science. A Theory proposes a minimal model…
LiteratureGenetic regulationCell differentiationEvolutionGenes
Lysogenic Bacteria as an Experimental Model at the Pasteur Institute (1915-1965)
By: Valerie Racine
| Published: Oct 10, 2014
Lysogenic bacteria, or virus-infected bacteria, were the primary experimental models used by scientists working in the laboratories of the Pasteur…
ContextInstitut Pasteur (Paris, France)BacteriaEscherichia coliMonod, Jacques
The Effects of Gene Regulation on Aging in Caenorhabditis elegans (2003)
By: Dasia Garcia
| Published: Feb 16, 2017
In 2003, molecular biology and genetics researchers Coleen T. Murphy, Steven A. McCarroll, Cornelia I. Bargmann, Andrew Fraser, Ravi S. Kamath, Julie…
Caenorhabditis elegansCaenorhabditisInsulin-like growth factor-binding proteinsIGF-Binding ProteinsGenetic regulation
The Hedgehog Signaling Pathway in Vertebrates
By: Dorothy Regan Haskett
| Published: Jun 27, 2016
The hedgehog signaling pathway is a mechanism that regulates cell growth and differentiation during embryonic development, called embryogenesis, in…
Drosophila melanogasterCyclopiaGenetic regulationZebra danioGenes
"A Genomic Regulatory Network for Development" (2002), by Eric H. Davidson, et al.
By: Justin M. Wolter
| Published: Oct 11, 2013
In 2002 Eric Davidson and his research team published 'A Genomic Regulatory Network for Development' in Science. The authors present the first…
LiteratureGene regulatory networksSystems BiologyGenetic regulationGenes
"Evolution and
Tinkering" (1977), by Francois Jacob
By: Valerie Racine
| Published: Oct 24, 2014
In his essay Evolution and Tinkering, published in Science in 1977, Francois Jacob argued that a common analogy between the process of evolution by…
LiteratureInstitut Pasteur (Paris, France)OperonsGenetic regulationNobel Prizes
Apoptosis in Embryonic Development
By: Zane Bartlett
| Published: Jun 08, 2017
Apoptosis, or programmed cell death, is a mechanism in embryonic development that occurs naturally in organisms. Apoptosis is a different process…
ApoptosisGenetic regulationCaenorhabditis elegansCellsGerm Cells