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In 1969, Roy J. Britten and Eric H. Davidson published Gene Regulation for Higher Cells: A Theory, in Science. A Theory proposes a minimal model…
LiteratureGenetic regulationCell differentiationEvolutionGenesThe Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes,…
Y ChromosomeTestisEmbryosChromosomesSex ChromosomesThe Y-chromosome is one of a pair of chromosomes that determine the genetic sex of individuals in mammals, some insects, and some plants. In the…
Y ChromosomeSex ChromosomesEmbryosDNAChromosomesThe hedgehog signaling pathway is a mechanism that directs the development of embryonic cells in animals, from invertebrates to vertebrates. The…
EmbryologyEmbryosWieschaus, Eric F.Cellular signal transductionDrosophila melanogasterIn 2006, Kazutoshi Takahashi and Shinya Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become…
Stem cells--ResearchStem CellsNobel PrizesEmbryologyDevelopmental BiologySir John Bertrand Gurdon further developed nuclear transplantation, the technique used to clone organisms and to create stem cells, while working in…
Cell nuclei--TransplantationCellsCloningStem CellsEmbryonic Stem CellsIn 2002 Eric Davidson and his research team published 'A Genomic Regulatory Network for Development' in Science. The authors present the first…
LiteratureGene regulatory networksSystems BiologyGenetic regulationGenesThe Notch signaling pathway is a mechanism in animals by which adjacent cells communicate with each other, conveying spatial information and genetic…
EmbryologyDevelopmental BiologyEmbryosCell differentiationNotch genesChristiane Nusslein-Volhard studied how genes control embryonic development in flies and in fish in Europe during the twentieth and twenty-first…
DrosophilaEmbryologyGenesMorphogenesisRNA polymerasesIn the twentieth and early twenty-first centuries, Gail Roberta Martin specialized in biochemistry and embryology, more specifically cellular…
EmbryosEmbryos--PhysiologyEmbryos--AnatomyBlastocystRetrovirus Infections