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The hedgehog signaling pathway is a mechanism that directs the development of embryonic cells in animals, from invertebrates to vertebrates. The…
EmbryologyEmbryosWieschaus, Eric F.Cellular signal transductionDrosophila melanogasterIn 2002 Eric Davidson and his research team published 'A Genomic Regulatory Network for Development' in Science. The authors present the first…
LiteratureGene regulatory networksSystems BiologyGenetic regulationGenesGolden Rice was engineered from normal rice by Ingo Potrykus and Peter Beyer in the 1990s to help improve human health. Golden Rice has an engineered…
TechnologyRiceBiotechnologyGenesMolecular BiologyIn 1969, Roy J. Britten and Eric H. Davidson published Gene Regulation for Higher Cells: A Theory, in Science. A Theory proposes a minimal model…
LiteratureGenetic regulationCell differentiationEvolutionGenesJulia Bell worked in twentieth-century Britain, discovered Fragile X Syndrome, and helped find heritable elements of other developmental and genetic…
Genetic Disordersfetal developmentRubella in pregnancyRubella virusHeredityBicoid is the protein product of a maternal-effect gene unique to flies of the genus Drosophila . In 1988 Christiane Nüsslein-Volhard identified…
Nüsslein-Volhard, C. (Christiane)EmbryosMorphogenesisTuring, Alan, 1912-1954Morgan, Thomas Hunt, 1866-1945Victor Ambros is a professor of molecular medicine at the University of Massachusetts Medical School, and he discovered the first microRNA (miRNA) in…
PeopleRNAGenesEmbryosCaenorhabditis elegansThe source-sink model, first proposed by biologist Francis Crick in 1970, is a theoretical system for how morphogens distribute themselves across…
Crick, Francis, 1916-2004Nobel Prize winnersEmbryosMorphogenesisGenesChristiane Nusslein-Volhard studied how genes control embryonic development in flies and in fish in Europe during the twentieth and twenty-first…
DrosophilaEmbryologyGenesMorphogenesisRNA polymerases