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Jennifer Doudna and Emmanuelle Charpentier’s Experiment About the CRISPR/cas 9 System’s Role in Adaptive Bacterial Immunity (2012)
By: Meilin Zhu
| Published: Oct 19, 2017
In 2012, Jennifer Doudna, Emmanuelle Charpentier from the University of California, Berkeley, in Berkeley, California, and Umeå University in Umeå,…
gene editingStreptococcus pyogenesTranscription Activator-Like Effector NucleasesscFV green fluorescent protein, recombinantClustered Regularly Interspaced Short Palindromic Repeats
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
Embryonic Sex Differentiation and Sex Hormones (1947), by Carl R. Moore
By: Mary Drago
| Published: May 03, 2014
In 1947, Carl Richard Moore, a researcher at the University of Chicago, in Chicago, Illinois, wrote Embryonic Sex Differentiation and Sex Hormones,…
LiteratureEndocrinologyHormones, SexGonadal Steroid HormonesFreemartinism
"The Developmental Capacity of Nuclei Taken from Intestinal Epithelium Cells of Feeding Tadpoles" (1962), by John B. Gurdon
By: Giselle Lee
| Published: Mar 16, 2017
In 1962 researcher John Bertrand Gurdon at the University of Oxford in Oxford, England, conducted a series of experiments on the developmental…
Cell nuclei--TransplantationGenetic EngineeringNuclear TransplantationUniversity College (University of Oxford)Xenopus laevis
The Meselson-Stahl Experiment (1957–1958), by Matthew Meselson and Franklin Stahl
By: Victoria Hernandez
| Published: Apr 18, 2017
In an experiment later named for them, Matthew Stanley Meselson and Franklin William Stahl in the US demonstrated during the 1950s the semi-…
DNA ReplicationMeselson, MatthewStahl, Franklin W.DNA--SynthesisDNA
HeLa Cell Line
By: Rohini Nott
| Published: Sep 18, 2020
The HeLa cell line was the first immortal human cell line that George Otto Gey, Margaret Gey, and Mary Kucibek first isolated from Henrietta Lacks…
HeLa CellsContinuous cell linesResearch EthicsInformed consent (Medical law)Cervix uteri--Cancer
Calvin Bridges’ Experiments on Nondisjunction as Evidence for the Chromosome Theory of Heredity (1913-1916)
By: Kevin Gleason
| Published: May 18, 2017
From 1913 to 1916, Calvin Bridges performed experiments that indicated genes are found on chromosomes. His experiments were a part of his doctoral…
DrosophilaHeredityInheritance of acquired charactersColumbia University--Graduate studentsMutation
"Transfer of Fetal Cells with Multilineage Potential to Maternal Tissue" (2004), by Kiarash Khosrotehrani et al.
By: Alexis Abboud
| Published: Nov 14, 2014
In 2004, a team of researchers at Tufts-New England Medical Center in Boston, Massachusetts, investigated the fetal cells that remained in the…
CellsStem CellsMaternal-Fetal ExchangeFetal cells from maternal bloodFetus
The Effects of Gene Regulation on Aging in Caenorhabditis elegans (2003)
By: Dasia Garcia
| Published: Feb 16, 2017
In 2003, molecular biology and genetics researchers Coleen T. Murphy, Steven A. McCarroll, Cornelia I. Bargmann, Andrew Fraser, Ravi S. Kamath, Julie…
Caenorhabditis elegansCaenorhabditisInsulin-like growth factor-binding proteinsIGF-Binding ProteinsGenetic regulation
Temperature-Dependent Sex Determination in Reptiles
By: Karla T. Moeller
| Published: Feb 01, 2013
The sex of a reptile embryo partly results from the production of sex hormones during development, and one process to produce those hormones depends…
Sex DifferentiationReproductionAdaptationfetal developmentEmbryology