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The First Successful Cloning of a Gaur (2000), by Advanced Cell Technology
By: Caroline Appleton
| Published: Jul 26, 2013
Advanced Cell Technology (ACT), a stem cell biotechnology company in Worcester, Massachusetts, showed the potential for cloning to contribute to…
Cell nuclei--TransplantationCloningGaurAdvanced Cell Technology (Firm)Embryos
Luc Antoine Montagnier (1932-2022)
By: Jarrett L. Joubert
| Published: Nov 03, 2022
Luc Montagnier studied viruses, the immune system, and cancer in France during the second half of the twentieth century. In his early career,…
AIDS vaccinesAIDS (Disease)AIDS malignanciesHIV-positive personsHIV (Viruses)
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
"Formation of Genetically Mosaic Mouse Embryos and Early Development of Lethal (t12/t12)-Normal Mosaics" (1964), by Beatrice Mintz
By: Adam R. Navis
| Published: Jan 13, 2009
The paper "Formation of Genetically Mosaic Mouse Embryos and Early Development of Lethal (t12/t12)-Normal Mosaics," by Beatrice Mintz, describes a…
Mintz, BeatriceExperimentsMice
CRISPR Acquired Resistance Against Viruses (2007)
By: Meilin Zhu
| Published: Nov 15, 2017
In 2007, Philippe Horvath and his colleagues explained how bacteria protect themselves against viruses at Danisco, a Danish food company, in Dangé-…
gene editingStreptococcus thermophilusvirusesBacteriaRNA
Gene Transfer Strategy Used to Treat Tay - Sachs Disease (2005), by Sabata Martino’s Research Group
By: Tiffany Nardi
| Published: Feb 21, 2017
In the early 2000s, Sabata Martino and a team of researchers in Italy and Germany showed that they could reduce the symptoms of Tay-Sachs in…
Tay-Sachs DiseaseVirus-vector relationshipsGloboid Cell LeukodystrophyGangliosidesGene Therapy
"On the Permanent Life of Tissues outside of the Organism" (1912), by Alexis Carrel
By: Lijing Jiang
| Published: May 06, 2012
'On the Permanent Life of Tissues outside of the Organism' reports Alexis Carrel's 1912 experiments on the maintenance of tissue in culture media. At…
Tissue cultureStem CellsStem cells--ResearchEmbryologyGerm Cells
"The Outgrowth of the Nerve Fiber as a Mode of Protoplasmic Movement" (1910), by Ross Granville Harrison
By: Adam R. Navis
| Published: Nov 13, 2007
In "The Outgrowth of the Nerve Fiber as a Mode of Protoplasmic Movement," Ross Granville Harrison explores the growth of nerve fibers in vitro. The…
ExperimentsNerve Growth FactorTissue culture
"β-Catenin Defines Head Versus Tail Identity During Planarian Regeneration and Homeostasis" (2007), by Kyle A. Gurley, Jochen C. Rink, and Alejandro Sánchez Alvarado
By: Mary E. Sunderland
| Published: Mar 15, 2010
Alejandro Sánchez Alvarado's laboratory group has employed molecular tools to investigate old questions about regeneration and as a result have…
RegenerationExperiments
"Experiments in Plant Hybridization" (1866), by Johann Gregor Mendel
By: Amanda Andrei
| Published: Sep 04, 2013
During the mid-nineteenth century, Johann Gregor Mendel experimented with pea plants to develop a theory of inheritance. In 1843, while a monk in the…
GeneticsPeasLegumesPhenotypePlant breeding