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Christopher Polge and Lionel Edward Aston Rowson’s Experiments on the Freezing of Bull Spermatozoa (1950–1952)
By: Bailey Renee
| Published: Dec 19, 2017
In 1952, researchers Christopher Polge and Lionel Edward Aston Rowson, who worked at the Animal Research Center in Cambridge, England, detailed…
GlycerinCryopreservationSpermatozoaMicroorganisms--CryopreservationExperiments
David Wildt's Domestic Cat and Cheetah Experiments (1978-1983)
By: Caroline Appleton
| Published: Dec 19, 2011
David Wildt's cheetah (Acinonyx jubatus) research from 1978-1983 became the foundation for the use of embryological techniques in endangered species…
Endangered SpeciesExperimentsCatsFertility
Robert Geoffrey Edwards's Study of Fertilization of Human Oocytes Matured in vitro, 1965 to 1969
By: Lijing Jiang
| Published: Mar 10, 2011
Robert Geoffrey Edwards, a British developmental biologist at University of Cambridge, began exploring human in vitro fertilization (IVF) as a way to…
Fertilization in VitroExperimentsReproductionFertilizationOocytes
Calvin Bridges’ Experiments on Nondisjunction as Evidence for the Chromosome Theory of Heredity (1913-1916)
By: Kevin Gleason
| Published: May 18, 2017
From 1913 to 1916, Calvin Bridges performed experiments that indicated genes are found on chromosomes. His experiments were a part of his doctoral…
DrosophilaHeredityInheritance of acquired charactersColumbia University--Graduate studentsMutation
Rock-Menkin Experiments
By: Stephen Ruffenach
| Published: Jan 13, 2009
Dr. John Rock, a doctor of obstetrics and gynecology in Boston, and Miriam Menkin, Rock s hired lab technician, were the first researchers to…
Fertilization in VitroExperimentsReproductionFertilization
Hermann Joseph Muller's Study of X-rays as a Mutagen, (1926-1927)
By: Kevin M. Gleason
| Published: Mar 07, 2017
Hermann Joseph Muller conducted three experiments in 1926 and 1927 that demonstrated that exposure to x-rays, a form of high-energy radiation, can…
X-raysRadiationGeneticsMutationDrosophila
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
A Series of YouTube Videos Detailing the “CRISPR Babies” Experiment (2018), by He Jiankui
By: Risa Aria Schnebly, Brianna Ellis
| Published: Jul 31, 2021
In 2018, He Jiankui uploaded a series of videos to a YouTube channel titled “The He Lab” that detailed one of the first instances of a successful…
Literaturegene editingGenome EditingCRISPR (Genetics)CRISPR-associated protein 9
“Effect of Vaginal Sildenafil on the Outcome of In Vitro Fertilization (IVF) After Multiple IVF Failures Attributed to Poor Endometrial Development” (2002), by Geoffrey Sher and Jeffrey Fisch
By: Alison Lane
| Published: Dec 22, 2020
Researchers Geoffrey Sher and Jeffrey Fisch gave Viagra, also known as sildenafil, to women undergoing fertility treatment to test whether the…
Fertility clinicsFertility, HumanHuman embryo--TransplantationEmbryo TransferSildenafil Citrate
Shoukhrat Mitalipov and Masahito Tachibana’s Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells (2009)
By: Giselle Lee
| Published: Jan 10, 2018
Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial Diseases