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Scientists use cerebral organoids, which are artificially produced miniature organs that represent embryonic or fetal brains and have many properties…
TechnologyMicrocephalyBrainNeuronsBrain--Diseases--Animal modelsThe Roscoe B. Jackson Laboratory, known commonly in the scientific field as the Jackson Laboratory, was founded by Clarence Cook Little in May 1929.…
OrganizationOrganizationsLaboratoriesMiceGeneticsIn 2012, Jennifer Doudna, Emmanuelle Charpentier from the University of California, Berkeley, in Berkeley, California, and Umeå University in Umeå,…
gene editingStreptococcus pyogenesTranscription Activator-Like Effector NucleasesscFV green fluorescent protein, recombinantClustered Regularly Interspaced Short Palindromic RepeatsIn 1969, Roy J. Britten and Eric H. Davidson published Gene Regulation for Higher Cells: A Theory, in Science. A Theory proposes a minimal model…
LiteratureGenetic regulationCell differentiationEvolutionGenesIn 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsConrad Hal Waddington was an embryologist and theoretical biologist. His early experimental work investigated aspects of embryonic induction and the…
EpigenomicsEpigeneticsBiographyCharles Benedict Davenport, Madison Grant, and Henry Fairfield Osborn founded the Galton Society for the Study of the Origin and Evolution of Man, or…
OrganizationEugenicsDavenport, Charles Benedict, 1866-1944Laughlin, Harry Hamilton, 1880-1943segregationIn 1947, Carl Richard Moore, a researcher at the University of Chicago, in Chicago, Illinois, wrote Embryonic Sex Differentiation and Sex Hormones,…
LiteratureEndocrinologyHormones, SexGonadal Steroid HormonesFreemartinismJulia Bell worked in twentieth-century Britain, discovered Fragile X Syndrome, and helped find heritable elements of other developmental and genetic…
Genetic Disordersfetal developmentRubella in pregnancyRubella virusHeredityIn 1881 British opthalmologist Warren Tay made an unusual observation. He reported a cherry-red spot on the retina of a one-year-old patient, a…
Tay-Sachs DiseaseCongenital DisordersHeredity