Nancy Goodman Brinker founded the largest breast cancer organization in the US, Susan G. Komen for the Cure, during the twentieth century. In 1982, Brinker created the organization, Susan G. Komen for the Cure, in memory of her sister, who had died of breast cancer two years earlier. During the early twentieth century, breast cancer was socially stigmatized, very few people discussed the disease, and there were limited treatment options available for those diagnosed with the disease. Breast cancer is one of the most prevalent forms of cancer and it affects almost 12 percent of women worldwide. In 1983, Brinker created the Susan G. Komen Race for Cure, a fundraising and awareness event for breast cancer. The organization provides funding for research, advocacy, and programs related to breast cancer. In the early 2000s, Brinker served as the US Ambassador to Hungary and, later, as the US Chief of Protocol. In 2009, US president Barack Obama awarded her the Presidential Medal of Freedom, the nation’s highest civilian honor. In 2017, Brinker serves as the Chair of Global Strategy at Susan G. Komen for the Cure and as the World Health Organization’s Goodwill Ambassador for Cancer Control. Brinker’s activism in the field of breast cancer raised awareness, public attention, funding, and support for women affected by breast cancer.