William Stewart Halsted was a surgeon at Johns Hopkins Hospital in Baltimore, Maryland, during the late 1800s and early 1900s. In 1894 Halsted described his procedure for treating breast cancer by removing the breast tissue, chest muscles, and lymph nodes in the armpit, a procedure he named radical mastectomy, and that became the standard of care for treating breast cancer until 1970. He also made contributions to other novel medical procedures such as gallbladder surgery, blood transfusions, antiseptic techniques, anesthesia use, and using plates and screws to hold bones in position when setting bone fractures. At Johns Hopkins Hospital, Halsted established a surgical training program in which he allowed medical students and surgical residents to shadow him and perform procedures under his guidance. In the twentieth century, similar training programs spread across the country and informed the standardization of medical training. Halsted devised a surgical treatment for breast cancer and reshaped the way physicians practiced medicine in the twentieth century, which resulted in better health outcomes through more careful surgical methods, especially in women with breast cancer.

Charles Richard Drew was an African American surgeon who helped improve blood transfusion practices during World War II and contributed to the development of modern-day blood banking. Sometimes called the Father of the Blood Bank, Drew showed that blood plasma, or the liquid component of blood, could be safely separated from whole blood, stored, and used for transfusion. Plasma has several advantages over whole blood, including that it can be stored safely for longer and transported over long distances. Drew’s methods allowed medics to treat thousands of injured Allied soldiers who were suffering from blood loss. Drew was also an advocate for racial desegregation in the United States and fought against the discriminatory blood donation practices of the American Red Cross. Drew’s work made blood transfusions safer and more accessible, which not only helped the Allied war effort in World War II, but also led to improvements in the treatment of complications during childbirth and efforts to reduce maternal mortality rates, particularly among Black women.