In 2010, Albert L. Hsu, Izebella Khchikyan, and Pamela Stratton published “Invasive and Non-invasive Methods for the Diagnosis of Endometriosis,” henceforth “Methods for the Diagnosis of Endometriosis,” in Clinical Obstetrics and Gynecology. In the article, the authors describe how specific types of endometriotic lesions appear in the body and evaluate five methods for diagnosing endometriosis. Endometriosis is the growth of endometrium, the tissue that normally lines the inside of the uterus, outside of the uterus. The authors state that although endometriosis impacts many women, the condition is difficult to identify. They identify laparoscopy, an invasive surgical procedure, as the most accurate diagnostic method. By analyzing the effectiveness of available diagnostic methods, the authors help physicians diagnose endometriosis and increase the quality of life for affected women.
Leuprolide acetate, or leuprorelin, is a manufactured drug that has been prescribed as a treatment for endometriosis, a medical condition in which body tissue that typically lines the uterus grows outside of the uterus, since 1989. Leuprorelin is a modified version of a gonadotropin-releasing hormone, a type of hormone that helps regulate the female menstrual cycle. The drug inhibits the production of estrogen, a female sex hormone that enables endometrial gland growth. After two weeks of injections, leuprorelin stops the production of estrogen, and without estrogen, endometrial glands become inactive. That decreases the growth of uterine tissue outside of the uterus, which helps decrease the pain associated with endometriosis. Although physicians commonly prescribe leuprorelin as of 2019, women with endometriosis have reported adverse side effects and health complications.
Laparoscopic tubal sterilization is a set of surgical techniques that use laparoscopy to render people with female reproductive systems sterile, or unable to reproduce. In a laparoscopy, a surgeon uses small incisions in the abdomen to feed in a camera or other viewing tool that aids in diagnosing internal medical issues or treating those issues via surgery. To sterilize a patient, the surgeon uses a camera with attached surgical tools to guide the procedure and interfere with the fallopian tubes to stop the passage of an egg. Laparoscopic sterilization was developed as an alternative to surgical sterilization that requires larger incisions to open the abdomen to access the fallopian tubes, which can pose a greater risk of complications. Due to decades of technical development, laparoscopic tubal sterilization allows people with female reproductive systems to control their fertility more safely and less invasively than with other surgical methods.