In 1928 Ezra Seymour Gosney founded the non-profit Human Betterment Foundation (HBF) in Pasadena, California to support the research and publication of the personal and social effects of eugenic sterilizations carried out in California. Led by director Gosney and secretary Paul Popenoe, the HBF collected data on thousands of individuals in California who had been involuntarily sterilized under a California state law enacted in 1909. The Foundation's assets were liquidated following Gosney's death in 1942. In 1943, Gosney's daughter donated the remaining assets to the California Institute of Technology (Caltech) in Pasadena, California to establish the Gosney research fund for biological research. Between 1928 and 1942, the HBF published extensively on what they believed to be the benefits of sterilization to both patient and society. The HBF and its members existed within the larger context of the American eugenics movement and scientific institutions, including the Eugenics Record Office at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York, which bolstered the movement's goals of the control of human reproduction and human heredity. Moreover, the model sterilization legislation written by the HBF was disseminated throughout the world to eugenics enthusiasts eager to pass laws limiting the reproduction of people they considered to be unfit.

In the 1973 case of Roe v. Wade, the US Supreme Court ruled that laws banning abortion violated the US Constitution. The Texas abortion laws, articles 1191–1194, and 1196 of the Texas penal code, made abortion illegal and criminalized those who performed or facilitated the procedure. Prior to Roe v. Wade, most states heavily regulated or banned abortions. The US Supreme Court decision in Roe v. Wade secured women's rights to terminate pregnancies for any reasons within the first trimester of pregnancy. It also sparked legal discussions of abortion, fetus viability and personhood, and the trimester framework, setting a landmark precedent for future cases including Webster v. Reproductive Health Services (1989), Planned Parenthood v. Casey (1992), and Stenberg v. Carhart (2000).

Jane Elizabeth Hodgson was a physician who advocated for abortion rights in the twentieth century in the United States. In November of 1970, Hodgson became the first physician in the U.S. to be convicted of performing an illegal abortion in a hospital. Hodgson deliberately performed the abortion to challenge the Minnesota State Statute 617.18, which prohibited non-therapeutic abortions. Following the legalization of abortion in the US Supreme Court case Roe v. Wade (1973), Hodgson focused on promoting accessible abortion, obstetric, and gynecological care throughout Minnesota. Her name also appears in the Supreme Court case Hodgson v. Minnesota (1990), which challenged the constitutionality of a Minnesota statute that required physicians to notify both parents forty-eight hours prior to a minor being allowed to undergoing an abortion. Hodgson’s career was centered around challenging the legal system to protect and promote reproductive rights for women, including access to abortion.

Lewis Madison Terman was a researcher and university professor who studied educational psychology and advocated for eugenics in the United States during the early twentieth century. The US eugenics movement, which Terman supported, was a collection of scientific research and social programs that aimed to improve human populations through control over human reproduction. One area many eugenicists studied was human intelligence as a means of determining how “desirable” a person may be. During the 1910s, while working at Stanford University in Palo Alto, California, Terman helped devise the Stanford-Binet scale for intelligence testing. As of 2024, the Stanford-Binet test is one of the main methods for providing individual intelligence quotient, or IQ, scores. In addition to the Stanford-Binet scale, Terman promoted the idea that individuals had fixed and inherited capacities for intelligence. Through both his development of a widely used method for measuring human intelligence and his promotion of the idea of intelligence as hereditary, Terman supported widespread social efforts to control human reproduction in the US during the twentieth century.