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Shoukhrat Mitalipov and Masahito Tachibana's Mitochondrial Gene Replacement Therapy Technique
By: Giselle Lee
| Published: Sep 06, 2017
In 2009, Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers developed the technology of mitochondrial gene replacement therapy to…
TechnologymonkeysGurdon, J. B. (John Bertrand)Briggs, Robert, -1983King, Thomas J. (Thomas Joseph), 1921-2000
"Formation of Genetically Mosaic Mouse Embryos and Early Development of Lethal (t12/t12)-Normal Mosaics" (1964), by Beatrice Mintz
By: Adam R. Navis
| Published: Jan 13, 2009
The paper "Formation of Genetically Mosaic Mouse Embryos and Early Development of Lethal (t12/t12)-Normal Mosaics," by Beatrice Mintz, describes a…
Mintz, BeatriceExperimentsMice
"β-Catenin Defines Head Versus Tail Identity During Planarian Regeneration and Homeostasis" (2007), by Kyle A. Gurley, Jochen C. Rink, and Alejandro Sánchez Alvarado
By: Mary E. Sunderland
| Published: Mar 15, 2010
Alejandro Sánchez Alvarado's laboratory group has employed molecular tools to investigate old questions about regeneration and as a result have…
RegenerationExperiments
Nuclear Transplantation
By: Sean Cohmer
| Published: Jun 14, 2011
Nuclear transplantation is a method in which the nucleus of a donor cell is relocated to a target cell that has had its nucleus removed (enucleated…
Cell nuclei--TransplantationNuclear Transplantation
"Experiments in Plant Hybridization" (1866), by Johann Gregor Mendel
By: Amanda Andrei
| Published: Sep 04, 2013
During the mid-nineteenth century, Johann Gregor Mendel experimented with pea plants to develop a theory of inheritance. In 1843, while a monk in the…
GeneticsPeasLegumesPhenotypePlant breeding
Cerebral Organoid as a Model System in the Study of Microcephaly
By: Dasia Garcia
| Published: May 12, 2017
Scientists use cerebral organoids, which are artificially produced miniature organs that represent embryonic or fetal brains and have many properties…
TechnologyMicrocephalyBrainNeuronsBrain--Diseases--Animal models
Elizabeth Dexter Hay (1927–2007)
By: Kevin Gleason
| Published: Jul 26, 2017
Elizabeth Dexter Hay studied the cellular processes that affect development of embryos in the US during the mid-twentieth and early twenty-first…
Electron microscopesExtracellular matrixCorneaCollagenRadioactive substances
Robert Alan Good (1922-2003)
By: Angel Lopez
| Published: Nov 16, 2010
Robert Alan Good was an American physician and scientific researcher who explored the cellular mechanisms of immunity. His research and discoveries…
PeopleBiographyImmunology
“Pregnancy Established in an Infertile Patient After Transfer of a Donated Embryo Fertilized In Vitro” (1983), by Alan Trounson, John Leeton, Mandy Besanko, Carl Wood, and Angelo Conti
By: Whitney Alexandra Tuoti
| Published: Apr 13, 2021
In 1983, researchers Alan Trounson, John Leeton, Carl Wood, Mandy Besanko, and Angelo Conti published the article “Pregnancy Established in an…
LiteratureFertilization in VitroIn vitro fertilizationEgg donorsTest-Tube Babies
Beatrice Mintz (1922–2022)
By: Adam R. Navis
| Published: Jan 21, 2009
Beatrice Mintz is a brilliant researcher who has developed techniques essential for many aspects of research on mouse development. She produced the…
PeopleBiographyMiceCancer