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In his essay Evolution and Tinkering, published in Science in 1977, Francois Jacob argued that a common analogy between the process of evolution by…
LiteratureInstitut Pasteur (Paris, France)OperonsGenetic regulationNobel PrizesIn 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsConrad Hal Waddington was an embryologist and theoretical biologist. His early experimental work investigated aspects of embryonic induction and the…
EpigenomicsEpigeneticsBiographyCharles Benedict Davenport, Madison Grant, and Henry Fairfield Osborn founded the Galton Society for the Study of the Origin and Evolution of Man, or…
OrganizationEugenicsDavenport, Charles Benedict, 1866-1944Laughlin, Harry Hamilton, 1880-1943segregationIn 1947, Carl Richard Moore, a researcher at the University of Chicago, in Chicago, Illinois, wrote Embryonic Sex Differentiation and Sex Hormones,…
LiteratureEndocrinologyHormones, SexGonadal Steroid HormonesFreemartinismJulia Bell worked in twentieth-century Britain, discovered Fragile X Syndrome, and helped find heritable elements of other developmental and genetic…
Genetic Disordersfetal developmentRubella in pregnancyRubella virusHeredityIn 1881 British opthalmologist Warren Tay made an unusual observation. He reported a cherry-red spot on the retina of a one-year-old patient, a…
Tay-Sachs DiseaseCongenital DisordersHeredityLap-Chee Tsui is a geneticist who discovered the cystic fibrosis (CF) gene, and his research team sequenced human chromosome 7. As the location of…
PeopleTsui, Lap-CheeCystic FibrosisReproductionBiographyFetal programming, or prenatal programming, is a concept that suggests certain events occurring during critical points of pregnancy may cause…
Diabetes in pregnancyMaternal-Fetal ExchangeMetabolism in pregnancyMaternal-Fetal MedicineMothers--NutritionWalter Jakob Gehring discovered the homeobox, a DNA segment found in a specific cluster of genes that determine the body plan of animals, plants, and…
Homeobox genesDrosophilaGeneticsGenesGenes, Homeobox