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In the late 1980s, Peter Goodfellow in London, UK led a team of researchers who showed that the SRY gene in humans codes a protein that causes testes…
TestisY ChromosomeEmbryosChromosomesSex ChromosomesCongenital rubella syndrome (CRS) can occur in children whose mothers contracted the rubella virus, sometimes called German measles, during pregnancy…
RubellaRubella in pregnancyRubella virusPregnancyEmbryosDevelopmental Effects of Endocrine-Disrupting Chemicals in Wildlife and Humans, was published in 1993 in Environmental Health Perspectives. In the…
LiteratureEndocrine disrupting chemicalsEmbryologyfetal developmentendocrine disruptorsIn his 1991 article Screening for Congenital Hypothyroidism, Delbert A. Fisher in the US reported on the implementation and impact of mass neonatal…
LiteratureCongenital HypothyroidismNewborn infants--DevelopmentCretinismInfant Health ServicesIn Australia in the 1940s, Norman McAlister Gregg observed a connection between pregnant women who contracted the rubella virus, or German measles,…
LiteratureCataract in childrenRubellaRubella in pregnancyRubella virusThe Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes,…
Y ChromosomeTestisEmbryosChromosomesSex ChromosomesIllustration of the animal-vegetal gradient in Xenopus laevis ( African clawed frog) eggs after fertilization.
BlastulaOrganismsIllustration of the movement of the three hemispheres of cells, the animal cap (dark green) the marginal zone (lime green) and the ventral cap (yel
BlastulaGastrulationEctodermEndodermOrganismsOswald Theodore Avery studied strains of pneumococcus of the genus Streptococcus in the US in the first half of the twentieth century. This bacterium…
Bacterial TransformationDNAHeredityPathologyImmunologyThe Cell-Theory was written by Thomas Henry Huxley in Britain and published in 1853 by The British and Foreign Medico-Chirurgical Review. The twenty-…
LiteratureEpigeneticsEmbryologyHuxley, Thomas Henry, 1825-1895Cellular control mechanisms