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Mitochondrial DNA (mtDNA) is located outside the nucleus in the liquid portion of the cell (cytoplasm) inside cellular organelles called Mitochondria…
Mitochondrial DNAMitochondriaMitochondrial DisordersMitochondrial pathologyMitochondrial DNA--AbnormalitiesLuc Montagnier studied viruses, the immune system, and cancer in France during the second half of the twentieth century. In his early career,…
AIDS vaccinesAIDS (Disease)AIDS malignanciesHIV-positive personsHIV (Viruses)In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsDavid Phillip Vetter was born with X-linked severe combined immunodeficiency disorder, or X-SCID, and spent most of his life in an isolated sterile…
X-Linked Combined Immunodeficiency DiseasesX-Linked SCIDSevere Combined ImmunodeficiencyBone Marrow--TransplantationAutoimmune DiseasesThe paper "Formation of Genetically Mosaic Mouse Embryos and Early Development of Lethal (t12/t12)-Normal Mosaics," by Beatrice Mintz, describes a…
Mintz, BeatriceExperimentsMiceBeatrice Mintz is a brilliant researcher who has developed techniques essential for many aspects of research on mouse development. She produced the…
PeopleBiographyMiceCancerStudies in Spermatogenesis is a two volume book written by Nettie Maria Stevens, and published by the Carnegie Institution of Washington in 1905 and…
LiteratureSpermatogenesisGenetic sex determinationSex DifferentiationEmbryosTelomeres are sequences of DNA on the ends of chromosomes that protect chromosomes from sticking to each other or tangling, which could cause…
TelomeraseGreider, Carol W.Wistar Institute of Anatomy and BiologyAgingDNAIn 2006, the article “HPV in the Etiology of Human Cancer,” hereafter “HPV and Etiology,” by Nubia Muñoz, Xavier Castellsagué, Amy Berrington de…
LiteraturePapillomavirusesCervix uteri--CancerVaccine mandatesMouth--CancerMitochondrial diseases in humans result when the small organelles called mitochondria, which exist in all human cells, fail to function normally. The…
Mitochondrial pathologyMitochondriaCell organellesCell nuclei--TransplantationReproductive technology