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"Presence of Fetal DNA in Maternal Plasma and Serum" (1997), by Dennis Lo, et al.
By: Cassidy Possehl
| Published: Mar 07, 2017
In the late 1990s researchers Yuk Ming Dennis Lo and his colleagues isolated fetal DNA extracted from pregnant woman’s blood. The technique enabled…
AmniocentesisChorionic Villus SamplingFetusObstetricsDNA
Noninvasive Fetal Aneuploidy Detection for Trisomy 21, 13, and 18
By: Cassidy Possehl
| Published: Apr 06, 2017
Noninvasive fetal aneuploidy detection technology allows for the detection of fetal genetic conditions, specifically having three chromosomes, a…
TechnologyDown syndromeAneuploidyLo, Y. M. DennisCleft Palate
Sanger Sequencing
By: Tea Zawilak
| Published: Aug 08, 2025
Sanger sequencing is a laboratory method that scientists use to determine the sequence of nucleotides within a piece of deoxyribonucleic acid, or DNA…
Sequence Analysis, DNAGenomicsPolymerase chain reactionNucleotide sequenceGenetics
Using Digital PCR to Detect Fetal Chromosomal Aneuploidy in Maternal Blood (2007)
By: Meilin Zhu
| Published: Nov 08, 2017
In 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidy
Allan Charles Wilson (1934-1991)
By: Dorothy Haskett
| Published: Jul 24, 2014
Allan C. Wilson studied genes, proteins, and body structures of animals and humans in the US during the second half of the twentieth century. Wilson…
Human EvolutionEvolutionChimpanzeesMitochondriaElectrophoresis