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The epigenetic landscape is a concept representing embryonic development. It was proposed by Conrad Hal Waddington to illustrate the various…
Waddington, C. H. (Conrad Hal), 1905-1975EpigeneticsCell differentiationEmbryologyDevelopmental BiologyConrad Hal Waddington's "Experiments on Embryonic Induction III," published in 1934 in the Journal of Experimental Biology, describes the discovery…
Waddington, C. H. (Conrad Hal), 1905-1975EmbryosCell differentiationEmbryologyChickens--EmbryosThe hedgehog signaling pathway is a mechanism that directs the development of embryonic cells in animals, from invertebrates to vertebrates. The…
EmbryologyEmbryosWieschaus, Eric F.Cellular signal transductionDrosophila melanogasterMesoderm is one of the three germ layers, groups of cells that interact early during the embryonic life of animals and from which organs and tissues…
MesodermGastrulationCell differentiationCellsTissuesRichard Woltereck first described the concept of Reaktionsnorm (norm of reaction) in his 1909 paper 'Weitere experimentelle Untersuchungen uber Art-…
Woltereck, Richard, 1877-1944EvolutionDaphniaEmbryologyHeredityWilhelm Johannsen in Denmark first proposed the distinction between genotype and phenotype in the study of heredity in 1909. This distinction is…
Johannsen, W. (Wilhelm), 1857-1927Genotype-environment interactionPhenotypeHeredityGeneticsEndoderm is one of the germ layers-- aggregates of cells that organize early during embryonic life and from which all organs and tissues develop.…
GastrulationEmbryosEmbryologyCellsTissuesFortunio Liceti studied natural philosophy and medicine in Italy during the first half of the seventeenth century. Liceti wrote greater than seventy…
TeratologyAbnormalities, HumanAnimals--AbnormalitiesEmbryologyPathologyCarl Richard Moore was a professor and researcher at the University of Chicago in Chicago, Illinois who studied sex hormones in animals from 1916…
Moore, Carl R. (Carl Richard), 1892-1955Intersexuality in animalsIntersex peopleHormones, SexSex DifferentiationThe Notch signaling pathway is a mechanism in animals by which adjacent cells communicate with each other, conveying spatial information and genetic…
EmbryologyDevelopmental BiologyEmbryosCell differentiationNotch genes