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The hedgehog signaling pathway is a mechanism that directs the development of embryonic cells in animals, from invertebrates to vertebrates. The…
EmbryologyEmbryosWieschaus, Eric F.Cellular signal transductionDrosophila melanogasterAmong other functions, the Notch signaling pathway forestalls the process of myogenesis in animals. The Notch signaling pathway is a pathway in…
MyogenesisNotch genesNotch ProteinsMusclesMyoblastsThe Notch signaling pathway is a mechanism in animals by which adjacent cells communicate with each other, conveying spatial information and genetic…
EmbryologyDevelopmental BiologyEmbryosCell differentiationNotch genesHilde Proscholdt Mangold was a doctoral student at the Zoological Institute at the University of Freiburg in Freiburg, Germany, from 1920-1923.…
LiteratureEmbryosTrembley, Abraham, 1710-1784GastrulationEmbryologyThe source-sink model, first proposed by biologist Francis Crick in 1970, is a theoretical system for how morphogens distribute themselves across…
Crick, Francis, 1916-2004Nobel Prize winnersEmbryosMorphogenesisGenesThe Spemann-Mangold organizer, also known as the Spemann organizer, is a cluster of cells in the developing embryo of an amphibian that induces…
EmbryosAmphibiansSpemann, Hans, 1869-1941EmbryologyGastrulation