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"Contributions to the Development of the Embryo. On the Artificial Production of One of the First Two Blastomeres, and the Later Development (Postgeneration) of the Missing Half of the Body" (1888), by Wilhelm Roux
By: Megan Kearl
| Published: Jul 20, 2009
Wilhelm Roux was an influential figure in the early history of experimental embryology. Although he originally studied medicine, he was invited to be…
LiteratureRoux, Wilhelm, 1850-1924ExperimentsFrogsOva
Calvin Bridges’ Experiments on Nondisjunction as Evidence for the Chromosome Theory of Heredity (1913-1916)
By: Kevin Gleason
| Published: May 18, 2017
From 1913 to 1916, Calvin Bridges performed experiments that indicated genes are found on chromosomes. His experiments were a part of his doctoral…
DrosophilaHeredityInheritance of acquired charactersColumbia University--Graduate studentsMutation
"Sheep Cloned by Nuclear Transfer from a Cultured Cell Line" (1996), by Keith Campbell, Jim McWhir, William Ritchie, and Ian Wilmut
By: Zane Bartlett
| Published: Sep 19, 2014
In 1995 and 1996, researchers at the Roslin Institute in Edinburgh, Scotland, cloned mammals for the first time. Keith Campbell, Jim McWhir, William…
CloningClone CellsCloning, MolecularCloning, OrganismExperiments
Amphioxus, and the Mosaic Theory of Development (1893), by Edmund Beecher Wilson
By: James Lowe
| Published: Mar 31, 2015
Edmund Beecher Wilson experimented with Amphioxus (Branchiostoma) embryos in 1892 to identify what caused their cells to differentiate into new types…
Wilson, Edmund B. (Edmund Beecher), 1856-1939AmphioxusEmbryosEmbryologyDevelopmental Biology
Hermann Joseph Muller's Study of X-rays as a Mutagen, (1926-1927)
By: Kevin M. Gleason
| Published: Mar 07, 2017
Hermann Joseph Muller conducted three experiments in 1926 and 1927 that demonstrated that exposure to x-rays, a form of high-energy radiation, can…
X-raysRadiationGeneticsMutationDrosophila
Thesis: How Purported Scientific Failures Have Led to Advancements in IVF
By: Whitney Alexandra Tuoti
| Published: Mar 17, 2021
This thesis shows us the history of how some of the first attempts at IVF in humans using various options such as donated egg cells and cryopreserved…
Fertilization in VitroIn vitro fertilizationScience in literatureMedical Laboratory SciencePublications
Edgar Allen and Edward A. Doisy's Extraction of Estrogen from Ovarian Follicles, (1923)
By: Brendan Van Iten
| Published: Mar 02, 2017
In the early 1920s, researchers Edgar Allen and Edward Adelbert Doisy conducted an experiment that demonstrated that ovarian follicles, which produce…
OvariesCorpus LuteumEndometriumEstrogenHormones, Sex
"Embryonic Stem Cell Lines Derived from Human Blastocytes" (1998), by James Thomson
By: Ke Wu
| Published: Feb 01, 2011
After becoming chief pathologist at the University of Wisconsin-Madison Wisconsin Regional Primate Center in 1995, James A. Thomson began his…
Stem CellsExperimentsPublicationsHuman Development
"Embryonic Stem Cell Lines Derived from Human Blastocytes" (1998), by James Thomson
By: Ke Wu
| Published: Feb 01, 2011
After becoming chief pathologist at the University of Wisconsin-Madison Wisconsin Regional Primate Center in 1995, James A. Thomson began his…
Stem CellsExperimentsPublicationsHuman Development
"The Potency of the First Two Cleavage Cells in Echinoderm Development. Experimental Production of Partial and Double Formations" (1891-1892), by Hans Driesch
By: Megan Kearl
| Published: Jan 01, 2012
Hans Adolf Eduard Driesch was a late-nineteenth and early-twentieth century philosopher and developmental biologist. In the spring of 1891 Driesch…
ExperimentsPublicationsSea Urchins