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Sex-determining Region Y in Mammals
By: Troy Cox
| Published: Dec 31, 2013
The Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes,…
Y ChromosomeTestisEmbryosChromosomesSex Chromosomes
Telomerase in Human Development
By: Zane Bartlett
| Published: Mar 23, 2015
Telomerase is an enzyme that regulates the lengths of telomeres in the cells of many organisms, and in humans it begins to function int the early…
TelomeraseTelomereDNAMolecular BiologySomatic embryogenesis
Interspecies SCNT-derived Humanesque Blastocysts
By: Sarah Taddeo, Jason S. Robert, Nicole Diehnelt
| Published: Jun 23, 2017
Since the 1950s, scientists have developed interspecies blastocysts in laboratory settings, but not until the 1990s did proposals emerge to engineer…
BlastocystDiseasesbioethicsTadpoleCell nuclei--Transplantation
The Y-Chromosome in Animals
By: Dorothy R. Haskett
| Published: May 28, 2015
The Y-chromosome is one of a pair of chromosomes that determine the genetic sex of individuals in mammals, some insects, and some plants. In the…
Y ChromosomeSex ChromosomesEmbryosDNAChromosomes
George Herbert Hitchings (1905–1998)
By: Eboni E. Andersun
| Published: Jun 25, 2024
George Herbert Hitchings researched and developed medications that targeted specific parts of DNA replication processes to treat cancers and various…
Nucleoside analogDNA ReplicationDrug DevelopmentAcyclovirPharmacology
“A Sex Chromosome Anomaly in a Case of Gonadal Dysgenesis (Turner’s Syndrome)” (1959), by Charles Edmund Ford, K. W Jones, Paul E. Polani, J. C De Almeida, and J. H Briggs
By: Megha Pillai
| Published: Aug 06, 2024
In 1959, Charles Edmund Ford and colleagues published “A Sex Chromosome Anomaly in a Case of Gonadal Dysgenesis (Turner’s Syndrome),” hereafter “A…
Turner SyndromeGonadal DysgenesisGonadal Dysgenesis, XOGonadal Dysgenesis, 45, XAbnormalities, Sex Chromosome
Cornelia Isabella Bargmann (1961- )
By: Dasia Garcia
| Published: Jun 19, 2017
Cornelia Isabella Bargmann studied the relationship between genes, neural circuits, and behavior in the roundworm Caenorhabditis elegans (C. elegans…
Drosophila melanogasterNeural circuitryNeurobiologyHER-2 geneHER-2 protein
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
Charles Robert Cantor (1942- )
By: Alexis Abboud
| Published: Jun 11, 2015
Charles Robert Cantor helped sequence the human genome, and he developed methods to non-invasively determine the genes in human fetuses. Cantor…
Human Genome ProjectDNAfetal developmentFetusEmbryos
Roy John Britten (1919-2012)
By: Abhinav Mishra
| Published: Oct 24, 2014
Roy John Britten studied DNA sequences in the US in the second half of the twentieth century, and he helped discover repetitive elements in DNA…
DNAGenomesCalifornia Institute of TechnologyGenetic regulationMice