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"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
Elizabeth Blackburn, Carol Greider and Jack Szostak's Telomere and Telomerase Experiments (1982-1989)
By: Zane Bartlett
| Published: Mar 24, 2015
Experiments conducted by Elizabeth Blackburn, Carol Greider, and Jack Szostak from 1982 to 1989 provided theories of how the ends of chromosomes,…
TelomereGreider, Carol W.Chromosome replicationTelomeraseDNA
"Presence of Fetal DNA in Maternal Plasma and Serum" (1997), by Dennis Lo, et al.
By: Cassidy Possehl
| Published: Mar 07, 2017
In the late 1990s researchers Yuk Ming Dennis Lo and his colleagues isolated fetal DNA extracted from pregnant woman’s blood. The technique enabled…
AmniocentesisChorionic Villus SamplingFetusObstetricsDNA
Induced Pluripotent Stem Cell Experiments by Kazutoshi Takahashi and Shinya Yamanaka in 2006 and 2007
By: Zane Bartlett
| Published: Jun 01, 2015
In 2006, Kazutoshi Takahashi and Shinya Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become…
Stem cells--ResearchStem CellsNobel PrizesEmbryologyDevelopmental Biology
The Hershey-Chase Experiments (1952), by Alfred Hershey and Martha Chase
By: Victoria Hernandez
| Published: Jun 23, 2019
In 1951 and 1952, Alfred Hershey and Martha Chase conducted a series of experiments at the Carnegie Institute of Washington in Cold Spring Harbor,…
BacteriophagesDNACold Spring Harbor LaboratoryProtein PrecursorsAmino Acid Sequence
Using Digital PCR to Detect Fetal Chromosomal Aneuploidy in Maternal Blood (2007)
By: Meilin Zhu
| Published: Nov 08, 2017
In 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidy
Oswald Theodore Avery (1877-1955)
By: Samantha Hauserman
| Published: Dec 12, 2013
Oswald Theodore Avery studied strains of pneumococcus of the genus Streptococcus in the US in the first half of the twentieth century. This bacterium…
Bacterial TransformationDNAHeredityPathologyImmunology
The Meselson-Stahl Experiment (1957–1958), by Matthew Meselson and Franklin Stahl
By: Victoria Hernandez
| Published: Apr 18, 2017
In an experiment later named for them, Matthew Stanley Meselson and Franklin William Stahl in the US demonstrated during the 1950s the semi-…
DNA ReplicationMeselson, MatthewStahl, Franklin W.DNA--SynthesisDNA