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In 1954 Max Delbruck published On the Replication of Desoxyribonucleic Acid (DNA) to question the semi-conservative DNA replication mechanism…
LiteratureHolmes, Frederic LawrenceMeselson, MatthewStahl, Franklin W.Watson, James D., 1928-In May 1953, scientists James Watson and Francis Crick wrote the article “Genetical Implications of the Structure of Deoxyribonucleic Acid,”…
LiteratureDNANucleic AcidsDeoxyriboseGeneticsOn 6 May 1952, at King’s College London in London, England, Rosalind Franklin photographed her fifty-first X-ray diffraction pattern of…
LiteratureDNADNA HelicasesX Ray CrystallographyCrystallography, X-RayIn 2001, Yale University Press published Frederic Lawrence Holmes' book, Meselson, Stahl, and the Replication of DNA: A History of "The Most…
LiteratureWatson, James D., 1928-Crick, Francis, 1916-2004Marine Biological Laboratory (Woods Hole, Mass.)DNA ReplicationIn April 1953, Rosalind Franklin and Raymond Gosling, published “Molecular Configuration in Sodium Thymonucleate,” in the scientific journal Nature.…
LiteratureDNADNA HelicasesX Ray CrystallographyMolecular structureIn April 1953, James Watson and Francis Crick published “Molecular Structure of Nucleic Acids: A Structure of Deoxyribose Nucleic Acid” or “A…
LiteratureDNAComplementary DNADNA ReplicationDeoxyribonucleic AcidIn February 1953, Linus Pauling and Robert Brainard Corey, two scientists working at the California Institute of Technology in Pasadena, California,…
LiteratureDNAGeneticsX-ray crystallography--TechniqueCrystallography, X-RayIn 2013, George Church and his colleagues at Harvard University in Cambridge, Massachusetts published RNA-Guided Human Genome Engineering via Cas 9,…
Literaturegene editingTranscription Activator-Like Effector NucleasesscFV green fluorescent protein, recombinantClustered Regularly Interspaced Short Palindromic RepeatsIn 1944, Oswald Avery, Colin MacLeod, and Maclyn McCarty published an article in which they concluded that genes, or molecules that dictate how…
LiteratureTransformation, BacterialBacterial TransformationStreptococcus pneumoniaeBacterial geneticsIn 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems