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In May 1953, scientists James Watson and Francis Crick wrote the article “Genetical Implications of the Structure of Deoxyribonucleic Acid,”…
LiteratureDNANucleic AcidsDeoxyriboseGeneticsIn the late 1990s researchers Yuk Ming Dennis Lo and his colleagues isolated fetal DNA extracted from pregnant woman’s blood. The technique enabled…
AmniocentesisChorionic Villus SamplingFetusObstetricsDNARosalind Elsie Franklin worked with X-ray crystallography at King's College London, UK, and she helped determine the helical structure of DNA in the…
PeopleDNAX-Ray CrystallographyMolecular geneticsMolecular BiologyOn 6 May 1952, at King’s College London in London, England, Rosalind Franklin photographed her fifty-first X-ray diffraction pattern of…
LiteratureDNADNA HelicasesX Ray CrystallographyCrystallography, X-RayMary-Claire King studied genetics in the US in the twenty-first century. King identified two genes associated with the occurrence of breast cancer,…
GeneticsBreast--Cancer--SusceptibilityBreast--Cancer--Prognosis--Statistical methods--CongressesBreast--Cancer--ResearchDNA fingerprintingIn 2006, Kazutoshi Takahashi and Shinya Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become…
Stem cells--ResearchStem CellsNobel PrizesEmbryologyDevelopmental BiologyIn 1951 and 1952, Alfred Hershey and Martha Chase conducted a series of experiments at the Carnegie Institute of Washington in Cold Spring Harbor,…
BacteriophagesDNACold Spring Harbor LaboratoryProtein PrecursorsAmino Acid SequenceIn 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidyFranklin William Stahl studied DNA replication, bacteriophages, and genetic recombination in the US during the mid-twentieth and early twenty-first…
DNA SequenceNucleotide sequenceDNA ReplicationDNA--SynthesisDNA replication--RegulationIn an experiment later named for them, Matthew Stanley Meselson and Franklin William Stahl in the US demonstrated during the 1950s the semi-…
DNA ReplicationMeselson, MatthewStahl, Franklin W.DNA--SynthesisDNA