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“A Proposed Structure for the Nucleic Acids” (1953) by Linus Pauling and Robert Brainard Corey
By: Victoria Hernandez
| Published: Aug 26, 2019
In February 1953, Linus Pauling and Robert Brainard Corey, two scientists working at the California Institute of Technology in Pasadena, California,…
LiteratureDNAGeneticsX-ray crystallography--TechniqueCrystallography, X-Ray
Equilibrium Density Gradient Centrifugation in Cesium Chloride Solutions Developed by Matthew Meselson and Franklin Stahl
By: Victoria Hernandez
| Published: Dec 19, 2017
Matthew Meselson, Franklin Stahl, and Jerome Vinograd, developed cesium chloride, or CsCl, density gradient centrifugation in the 1950s at the…
TechnologyDNA ReplicationDNA replication--RegulationCentrifugation, Density GradientOrganonitrogen compounds
The Meselson-Stahl Experiment (1957–1958), by Matthew Meselson and Franklin Stahl
By: Victoria Hernandez
| Published: Apr 18, 2017
In an experiment later named for them, Matthew Stanley Meselson and Franklin William Stahl in the US demonstrated during the 1950s the semi-…
DNA ReplicationMeselson, MatthewStahl, Franklin W.DNA--SynthesisDNA
Categorization of Conservative, Semi-Conservative, and Dispersive DNA Replication Theories (1953–1956)
By: Victoria Hernandez
| Published: Oct 31, 2019
In 1956, Gunther Stent, a scientist at the University of California Berkeley in Berkeley, California, coined the terms conservative, semi-…
DNADNA ReplicationDNA HelicasesGenesHeredity
Meselson, Stahl, and the Replication of DNA: A History of "The Most Beautiful Experiment in Biology" (2001), by Frederic Lawrence Holmes
By: Victoria Hernandez
| Published: Jul 23, 2017
In 2001, Yale University Press published Frederic Lawrence Holmes' book, Meselson, Stahl, and the Replication of DNA: A History of "The Most…
LiteratureWatson, James D., 1928-Crick, Francis, 1916-2004Marine Biological Laboratory (Woods Hole, Mass.)DNA Replication
Matthew Stanley Meselson (1930– )
By: Victoria Hernandez
| Published: May 23, 2017
Matthew Stanley Meselson conducted DNA and RNA research in the US during the twentieth and twenty-first centuries. He also influenced US policy…
Holmes, Frederic LawrenceMeselson, MatthewStahl, Franklin W.Watson, James D., 1928-Crick, Francis, 1916-2004
Franklin William Stahl (1929– )
By: Victoria Hernandez
| Published: Jul 20, 2017
Franklin William Stahl studied DNA replication, bacteriophages, and genetic recombination in the US during the mid-twentieth and early twenty-first…
DNA SequenceNucleotide sequenceDNA ReplicationDNA--SynthesisDNA replication--Regulation
"On the Replication of Desoxyribonucleic Acid (DNA)" (1954), by Max Delbruck
By: Victoria Hernandez
| Published: Sep 21, 2017
In 1954 Max Delbruck published On the Replication of Desoxyribonucleic Acid (DNA) to question the semi-conservative DNA replication mechanism…
LiteratureHolmes, Frederic LawrenceMeselson, MatthewStahl, Franklin W.Watson, James D., 1928-
“Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid” (1953), by James Watson and Francis Crick
By: Victoria Hernandez
| Published: Oct 31, 2019
In April 1953, James Watson and Francis Crick published “Molecular Structure of Nucleic Acids: A Structure of Deoxyribose Nucleic Acid” or “A…
LiteratureDNAComplementary DNADNA ReplicationDeoxyribonucleic Acid
The Debate over DNA Replication Before the Meselson-Stahl Experiment (1953–1957)
By: Victoria Hernandez
| Published: Jan 03, 2018
Between 1953 and 1957, before the Meselson-Stahl experiment verified semi-conservative replication of DNA, scientists debated how DNA replicated. In…
ChromosomesCalifornia Institute of TechnologyCold Spring Harbor LaboratoryDNA Replication