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"Cell Deaths in Normal Vertebrate Ontogeny" (1951), by Alfred Glücksmann
By: Lijing Jiang
| Published: Dec 06, 2010
The review article “Cell Deaths in Normal Vertebrate Ontogeny” (abbreviated as “Cell Deaths”) was published in Biological Reviews of the Cambridge…
LiteratureCell DeathPublicationsVertebratesOntogeny
"On the Permanent Life of Tissues outside of the Organism" (1912), by Alexis Carrel
By: Lijing Jiang
| Published: May 06, 2012
'On the Permanent Life of Tissues outside of the Organism' reports Alexis Carrel's 1912 experiments on the maintenance of tissue in culture media. At…
Tissue cultureStem CellsStem cells--ResearchEmbryologyGerm Cells
The Discovery of p53 Protein
By: Lijing Jiang
| Published: Jan 21, 2011
The p53 protein acts as a pivotal suppressor of inappropriate cell proliferation. By initiating suppressive effects through induction of apoptosis,…
Tumor Suppressor Protein p53ExperimentsCancerCell Death
Alexis Carrel's Tissue Culture Techniques
By: Lijing Jiang
| Published: Jun 18, 2010
Alexis Carrel, the prominent French surgeon, biologist, and 1912 Nobel Prize laureate for Physiology or Medicine, was one of the pioneers in…
TechnologyCarrel, Alexis, 1873-1944Tissue Culture TechniquesTissue culture
Michael D. West (1953- )
By: Lijing Jiang
| Published: Jun 23, 2010
Michael D. West is a biomedical entrepreneur and investigator whose aim has been to extend human longevity with biomedical interventions. His focus…
PeopleStem CellsBiographyRegeneration
"Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics" (1972), by John F. R. Kerr, Andrew H. Wyllie and Alastair R. Currie
By: Lijing Jiang
| Published: Jan 21, 2011
"Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics" (hereafter abbreviated as "Apoptosis") was published in…
LiteratureApoptosisPublicationsCancerCell Death
Viktor Hamburger's Study of Central-Peripheral Relations in the Development of Nervous System
By: Lijing Jiang
| Published: Nov 19, 2010
An important question throughout the history of embryology is whether the formation of a biological structure is predetermined or shaped by its…
Hamburger, Viktor, 1900-2001ExperimentsNervous SystemCell Death
"Cellular death in morphogenesis of the avian wing" (1962), by John W. Saunders Jr., et al.
By: Lijing Jiang
| Published: Mar 07, 2014
In the early 1960s, John W. Saunders Jr., Mary T. Gasseling, and Lilyan C. Saunders in the US investigated how cells die in the developing limbs of…
Cell DeathChickens--EmbryosApoptosisExperiments
"The Effects of Wing Bud Extirpation on the Development of the Central Nervous System in Chick Embryos" (1934), by Viktor Hamburger
By: Lijing Jiang
| Published: Nov 22, 2010
German embryologist Viktor Hamburger came to the US in 1932 with a fellowship provided by the Rockefeller Foundation. Hamburger started his research…
LiteraturePublicationsExperimentsNervous SystemChicks
"Programmed Cell Death-II. Endocrine Potentiation of the Breakdown of the Intersegmental Muscles of Silkmoths" (1964), by Richard A. Lockshin and Carroll M. Williams
By: Lijing Jiang
| Published: Apr 27, 2011
Richard A. Lockshin's 1963 PhD dissertation on cell death in insect metamorphosis was conducted under the supervision of Harvard insect physiologist…
LiteratureExperimentsPublicationsSilkwormsHormones