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Apoptosis, or programmed cell death, is a mechanism in embryonic development that occurs naturally in organisms. Apoptosis is a different process…
ApoptosisGenetic regulationCaenorhabditis elegansCellsGerm CellsIn the early 1960s, John W. Saunders Jr., Mary T. Gasseling, and Lilyan C. Saunders in the US investigated how cells die in the developing limbs of…
Cell DeathChickens--EmbryosApoptosisExperimentsAn important question throughout the history of embryology is whether the formation of a biological structure is predetermined or shaped by its…
Hamburger, Viktor, 1900-2001ExperimentsNervous SystemCell DeathThe review article “Cell Deaths in Normal Vertebrate Ontogeny” (abbreviated as “Cell Deaths”) was published in Biological Reviews of the Cambridge…
LiteratureCell DeathPublicationsVertebratesOntogenyThe HeLa cell line was the first immortal human cell line that George Otto Gey, Margaret Gey, and Mary Kucibek first isolated from Henrietta Lacks…
HeLa CellsContinuous cell linesResearch EthicsInformed consent (Medical law)Cervix uteri--Cancer"Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics" (hereafter abbreviated as "Apoptosis") was published in…
LiteratureApoptosisPublicationsCancerCell DeathThe Hayflick Limit is a concept that helps to explain the mechanisms behind cellular aging. The concept states that a normal human cell can only…
CellsCell populationsCell DeathApoptosisCell ProliferationOnce perceived as an unimportant occurrence in living organisms, cell degeneration was reconfigured as an important biological phenomenon in…
Cell DeathCells--AgingCaenorhabditis elegansAging, CellCellular AgingLeonard Hayflick studied the processes by which cells age during the twentieth and twenty-first centuries in the United States. In 1961 at the Wistar…
PeopleCellsCell populationsCell DeathApoptosisIn an effort to develop tissue culture techniques for long-term tissue cultivation, French surgeon and biologist Alexis Carrel, and his associates,…
Carrel, Alexis, 1873-1944Tissue cultureCellsGerm CellsEmbryos