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Ectopic Pregnancy
Many difficulties can arise with a pregnancy even after the sperm successfully fertilizes the oocyte. A major problem occurs if the fertilized egg tries to implant before reaching its normal implantation site, the uterus. An ectopic pregnancy occurs when a fertilized egg implants anywhere other than in the uterus, most commonly in the fallopian tubes. Ectopic pregnancies cannot continue to term, so a physician must remove the developing embryo as early as possible.
Format: Articles
Subject: Disorders, Processes, Reproduction
Pregnancy Tests
Throughout history methods involving urine have been a popular way to test for pregnancy. Early ideas ranged from simply observing the color of a woman's urine to the notion that the urine of pregnant women contains special crystals or secretions. Indeed, pregnancy testing can be traced back to 1350 BCE in Ancient Egypt. A written document from the time describes a process in which a woman would urinate on wheat and barley seeds over several days and, depending on which plant grew, both the woman's pregnancy status and the sex of the fetus could be determined.
Format: Articles
Subject: Technologies, Reproduction
Multi-Fetal Pregnancy
In humans, multi-fetal pregnancy occurs when a mother carries more than one fetus during the pregnancy. The most common multi-fetal pregnancy is twins, but mothers have given birth to up to eight children (octuplets) from a single pregnancy. Multiple fetusus can result from the release of multiple eggs or multiple ovulations, the splitting of a single fertilized egg, and fertility treatments such as in vitro fertilization (IVF) which involves the insertion of many fertilized eggs into the mother's uterus.
Format: Articles
Subject: Processes, Reproduction
The Aschheim-Zondek Test for Pregnancy
Throughout history many different methods have been devised for the early detection of pregnancy. From the time of the Ancient Egyptians, inspection of the urine has been a popular place to start. However, it was not until the discovery of hormones in the early twentieth century that the development of truly reliable pregnancy tests occurred. Prior to 1978, when the first home pregnancy tests became available in the United States, pregnancy testing was done in hospital laboratories using various methods, one of them being the Aschheim-Zondek, or A-Z test.
Format: Articles
Subject: Technologies, Reproduction
Rh Incompatibility in Pregnancy
Rh incompatibility occurs when a pregnant woman whose blood type is Rh-negative is exposed to Rh-positive blood from her fetus, leading to the mother s development of Rh antibodies. These antibodies have the potential to cross the placenta and attach to fetal red blood cells, resulting in hemolysis, or destruction of the fetus 's red blood cells. This causes the fetus to become anemic, which can lead to hemolytic disease of the newborn. In severe cases, an intrauterine blood transfusion for the fetus may be required to correct the anemia.
Format: Articles
Subject: Processes, Disorders, Reproduction
“Of Pregnancy and Progeny” (1980), by Norbert Freinkel
Norbert Freinkel’s lecture Of Pregnancy and Progeny was published by the American Diabetes Association’s journal Diabetes in December of 1980. In the lecture, Freinkel argued that pregnancy changes the way that the female body breaks down and uses food. Through experiments that involved pregnant women as well as infants, Freinkel established the body’s maternal metabolism and how it affects both the mother and the infant. Freinkel’s main focus of research in the latter part of his life was diabetes, specifically in pregnant women.
Format: Articles
Subject: Publications
Hypertensive Disorders in Pregnancy (1978), by Leon Chesley
Leon Chesley published Hypertensive Disorders in Pregnancy in 1978 to outline major and common complications that occur during pregnancy and manifest in abnormally high blood pressures in pregnant women. The book was published by Appleton-Century-Crofts in New York, New York. Chesley compiled his book as a tool for practicing obstetricians and teachers.
Format: Articles
Subject: Publications
Treatment of Anemia during Pregnancy (1931), by Lucy Wills
In 1931, physician Lucy Wills conducted a study of nutritional deficiencies that caused anemia in pregnant women in Bombay, India, later renamed Mumbai. Anemia is a lack of healthy red blood cells in the blood. Wills published the results of her study in the medical article 'Treatment of ‘Pernicious Anaemia of Pregnancy' and 'Tropical Anaemia'' in the British Medical Journal in 1931. Wills's research contributed to knowledge of anemia and the possible causes associated with the disease, such as the symptoms of fatigue and irritability.
Format: Articles
Subject: Experiments
"Pregnancy Complicating Diabetes" (1949), by Priscilla White
In 1949, Priscilla White published Pregnancy Complicating Diabetes, which described the results and implications of a fifteen-year study about pregnant diabetic women. Published in the American Journal of Medicine, the article details possible causes of and ways to prevent the high fetal mortality rate associated with pregnant diabetic women. Diabetes is a disease in which the body's ability to produce or respond to the hormone insulin is impaired, and it can be particularly dangerous during pregnancies.
Format: Articles
Subject: Publications
Neural Tube Defects (NTD): Folic Acid and Pregnancy
In the US, one in 1000 births is affected by neural tube defects (NTD). A neural tube defect is a birth defect involving the malformation of body features associated with the brain and spinal cord. An NTD originates from and is characterized by incomplete closure of the neural tube, which is an organizer and precursor of the central nervous system.
Format: Articles
Subject: Disorders, Reproduction
"The Familial Factor in Toxemia of Pregnancy" (1968), by Leon C. Chesley, et al.
In the 1950s and 1960s, researchers Leon Chesley, John Annitto, and Robert Cosgrove investigated the possible familial factor for the conditions of preeclampsia and eclampsia in pregnant women. Preeclampsia and eclampsia, which are related to high blood pressure, have unknown causes and affect at least five percent of all pregnancies.
Format: Articles
Subject: Reproduction, Experiments, Disorders
“Diethylstilbestrol in the Prevention and Treatment of Complications of Pregnancy” (1948), by Olive Watkins Smith
In 1948, Olive Watkins Smith published 'Diethylstilbestrol in the Prevention and Treatment of Complications of Pregnancy' in the American Journal of Obstetrics and Gynecology. In 632 women treated with diethylstilbestrol, Smith demonstrated that the drug stimulated the production of progesterone, a hormone that regulates the uterine condition during pregnancy.
Format: Articles
Subject: Publications
"Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants" (2010), by Scott Sicherer, et al.
In 2010, a team of US researchers concluded that the more peanuts a pregnant woman ate during her pregnancy, the more likely her newborn was to be sensitive to peanuts. They published their results in 2010's "Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants." The work resulted from the collaboration of Scott Sicherer and Hugh Sampson, both from the Jaffe Food Allergy Institute, Mount Sinai School of Medicine, in New York, New York along with other colleagues.
Format: Articles
Subject: Experiments, Reproduction
Ginger as a Treatment for Nausea and Vomiting in Pregnancy by Teraporn Vutyavanich, Theerajana Kraisarin, and Rung-Aroon Ruangsri (1998–2001)
In 1998 and 1999, Teraporn Vutyavanich, Theerajana Kraisarin, and Rung-Aroon Ruangsri in Thailand showed that ginger alleviated nausea in pregnant women. Vutyavanich and his colleagues found that the group of pregnant women who took ginger capsules reported significantly fewer nausea symptoms and vomiting episodes than the group who only received the placebo. Vutyavanich and his team’s study at Chiang Mai University in Chiang Mai, Thailand, was one of the earliest to investigate and support the use of ginger as an effective treatment for relieving pregnancy-related nausea and vomiting.
Format: Articles
Subject: Experiments
"Maternal Thyroid Deficiency During Pregnancy and Subsequent Neuropsychological Development of the Child" (1999), by James E. Haddow et al.
From 1987 to the late 1990s, James Haddow and his team of researchers at the Foundation for Blood Research in Scarborough, Maine, studied children born to women who had thyroid deficiencies while pregnant with those children. Haddow's team focused the study on newborns who had normal thyroid function at the time of neonatal screening. They tested the intelligence quotient, or IQ, of the children, ages eight to eleven years, and found that all of the children born to thyroid-hormone deficient mothers performed less well than the control group.
Format: Articles
Subject: Experiments
Our Bodies, Ourselves (1973), by the Boston Women's Health Book Collective
Our Bodies, Ourselves, a succession to a pamphlet of resources pulled from co-ops of women in and around Boston, Massachusetts was published in New York in 1973 by Simon and Schuster. Retitled from the original Women and Their Bodies, Our Bodies, Ourselves was an effort by a group of educated, middle class women to reinforce women's ownership of their bodies. There have been eight editions of Our Bodies, Ourselves, as well as sequels such as Our Bodies, Ourselves: Pregnancy and Birth and Our Bodies, Ourselves: Menopause.
Format: Articles
Subject: Outreach, Reproduction
Ferguson v. City of Charleston (2001)
The US Supreme Court case Ferguson v. City of Charleston (2001) established that public hospitals couldn't legally drug test pregnant women without their consent when those women sought prenatal care at those hospitals. The court held that such searches violated the pregnant women's protections under the Fourth Amendment to the US Constitution. The decisions also indicated those circumstances that qualified as special needs exceptions to the Fourth Amendment, and it highlighted the extent to which pregnant women are sovereign individuals in the eyes of the Court. Ferguson v.
Format: Articles
Subject: Legal
"National Institutes of Health Consensus Development Conference Statement September 22–24, 1980” (1980), by the National Institutes of Health
In 1980 the US National Institutes of Health (NIH) and the US National Institute of Child Health and Human Development (NICHD) released a report titled, “National Institutes of Health Consensus Development Conference Statement September 22–24, 1980.” The report lists recommendations for birth delivery through cesarean sections, a surgical procedure used to deliver the fetus via the pregnant woman’s abdomen. The recommendations arose from the 1980 Consensus Development Conference on Cesarean Childbirth in Bethesda, Maryland.
Format: Articles
Subject: Publications
Leon Chesley (1908-2000)
Leon Chesley studied hypertension, or high blood pressure, in pregnant women during the mid-twentieth century. Chesley studied preeclampsia and eclampsia, two hypertensive disorders found in approximately five percent of all US pregnancies. In New Jersey and New York, Chesley devoted over forty years to researching preeclampsia and eclampsia. Chesley conducted several long-term studies using the same group of women beginning from their pregnancies.
Format: Articles
Subject: People, Reproduction
Anencephaly
Anencephaly is an open neural tube defect, meaning that part of the neural tube does not properly close or that it has reopened during early embryogenesis. An embryo with anencephaly develops without the top of the skull, but retains a partial skull, including the face. Anencephaly is one of the most common birth defects of the neural tube, occurring at a rate of approximately one in one thousand human pregnancies. The condition can be caused by environmental exposure to chemicals, dietary deficiencies, or genetic mutations.
Format: Articles
Subject: Disorders, Reproduction
Virginia Apgar (1909-1974)
Virginia Apgar worked as an obstetrical anesthesiologist, administering drugs that reduce women’s pain during childbirth, in the US in the mid-twentieth century. In 1953, Apgar created a scoring system using five easily assessable measurements, including heart rate and breathing rate, to evaluate whether or not infants would benefit from medical attention immediately after birth. Apgar’s system showed that infants who were previously set aside as too sick to survive, despite low Apgar scores, could recover with immediate medical attention.
Format: Articles
Subject: People, Reproduction
The China-US Study on the Prevention of Neural Tube Defects using Folic Acid (1999)
From 1993 to 1995 researchers led by Robert J. Berry from the US Centers for Disease Control headquartered in Atlanta, Georgia, and Zhu Li from Beijing Medical University in Beijing, China, conducted a collaborative study in China on the prevention of neural tube defects or NTDs using folic acid supplements. NTDs are birth defects in which openings in the spinal cord or the brain that occur during early development remain after birth. Neural-tube formation occurs in early pregnancy, often before a woman knows she is pregnant and therefore before she has begun taking prenatal vitamins.
Format: Articles
Subject: Experiments
Barry Morris Goldwater (1909–1998)
Barry Morris Goldwater was a Republican Arizona Senator and US presidential candidate in the twentieth-century whose policies supported the women's reproductive rights movement. Goldwater, a businessman and Air Force reservist, transitioned into politics in the 1950s. He helped align popular support for a conservative Republican Party in the 1960s. Throughout his life, he worked to maintain personal liberty and to limit governmental intrusion into citizens' private lives. Goldwater, influenced by his wife Margaret (Peggy) Goldwater, supported women's rights to abortions.
Format: Articles
Subject: People, Reproductive Health Arizona, Reproduction, Legal, Religion
Elinor Catherine Hamlin (1924- )
Elinor Catherine Hamlin founded and helped fund centers in Ethiopia to treat women affected by fistulas from obstetric complications. Obstetric fistulas develop in women who experience prolonged labor, as the pressure placed on the pelvis by the fetus during labor causes a hole, or fistula, to form between the vagina and the bladder (vesicovaginal fistula) or between the vagina and the rectum (rectovaginal fistula). Both of those conditions result in urinary or fecal incontinence, which often impacts womenÍs social status within their communities.
Format: Articles
Subject: People, Reproduction