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Purkinje cells, also called Purkinje neurons, are neurons in vertebrate animals located in the cerebellar cortex of the brain. Purkinje cell bodies…
Purkinje CellsCerebellar CortexcerebellumBrain StemJohn D. Gearhart is a renowned American developmental geneticist best known for leading the Johns Hopkins University research team that first…
PeopleStem CellsGeneticsBiographyIn the early 2000s, Sabata Martino and a team of researchers in Italy and Germany showed that they could reduce the symptoms of Tay-Sachs in…
Tay-Sachs DiseaseVirus-vector relationshipsGloboid Cell LeukodystrophyGangliosidesGene TherapyIn 2005, Ernest McCulloch and James Till published the article “Perspectives on the Properties of Stem Cells,” which discusses the various properties…
LiteratureStem CellsEmbryonic Stem CellsSomatic Stem CellsStem cells--ResearchMagnetic Resonance Microscopy (MRM) is an imaging method that allows the visualization of internal body structures. Using powerful magnets to send…
TechnologyMagnetic resonance microscopyMagnetic resonance imagingMicroscopyIntroduced by Conrad Hal Waddington in 1942, the concept of epigenetics gave scientists a new paradigm of thought concerning embryonic development,…
EpigenomicsEpigeneticsTranslational developmental biology is a growing approach to studying biological phenomena that explicitly aims to develop medical therapies. When…
medicineStem CellsEpidermal growth factor is a signaling molecule that stimulates the growth of epidermal tissues during development and throughout life. Stanley Cohen…
Levi-Montalcini, RitaHamburger, Viktor, 1900-2001EmbryologyEmbryosDevelopmental BiologyFrederik Ruysch, working in the Netherlands, introduced the term epithelia in the third volume of his Thesaurus Anatomicus in 1703. Ruysch created…
EpitheliumRuysch, Frederik, 1638-1731AnatomyCells--MorphologyHis, Wilhelm, 1831-1904The p53 protein acts as a pivotal suppressor of inappropriate cell proliferation. By initiating suppressive effects through induction of apoptosis,…
Tumor Suppressor Protein p53ExperimentsCancerCell Death