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"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
San Diego Zoo Institute for Conservation Research
By: Karen Love
| Published: Jun 12, 2017
The San Diego Zoo Institute for Conservation Research (SDZICR) in San Diego, California, is a research organization that works to generate, use, and…
OrganizationpreservationGeneticsEndangered SpeciesDNA
Telomerase in Human Development
By: Zane Bartlett
| Published: Mar 23, 2015
Telomerase is an enzyme that regulates the lengths of telomeres in the cells of many organisms, and in humans it begins to function int the early…
TelomeraseTelomereDNAMolecular BiologySomatic embryogenesis
Telomeres and Telomerase in Cellular Aging (Senescence)
By: Zane Bartlett
| Published: Feb 11, 2015
Telomeres are sequences of DNA on the ends of chromosomes that protect chromosomes from sticking to each other or tangling, which could cause…
TelomeraseGreider, Carol W.Wistar Institute of Anatomy and BiologyAgingDNA
Interspecies SCNT-derived Humanesque Blastocysts
By: Sarah Taddeo, Jason S. Robert, Nicole Diehnelt
| Published: Jun 23, 2017
Since the 1950s, scientists have developed interspecies blastocysts in laboratory settings, but not until the 1990s did proposals emerge to engineer…
BlastocystDiseasesbioethicsTadpoleCell nuclei--Transplantation
Induced Pluripotent Stem Cell Experiments by Kazutoshi Takahashi and Shinya Yamanaka in 2006 and 2007
By: Zane Bartlett
| Published: Jun 01, 2015
In 2006, Kazutoshi Takahashi and Shinya Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become…
Stem cells--ResearchStem CellsNobel PrizesEmbryologyDevelopmental Biology
The Y-Chromosome in Animals
By: Dorothy R. Haskett
| Published: May 28, 2015
The Y-chromosome is one of a pair of chromosomes that determine the genetic sex of individuals in mammals, some insects, and some plants. In the…
Y ChromosomeSex ChromosomesEmbryosDNAChromosomes
“Studies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types: Induction of Transformation by a Desoxyribonucleic Acid Fraction Isolated from Pneumococcus Type III” (1944) by Oswald Avery, Colin MacLeod and Maclyn McCarty
By: Victoria Hernandez
| Published: Jul 08, 2019
In 1944, Oswald Avery, Colin MacLeod, and Maclyn McCarty published an article in which they concluded that genes, or molecules that dictate how…
LiteratureTransformation, BacterialBacterial TransformationStreptococcus pneumoniaeBacterial genetics
Sex-determining Region Y in Mammals
By: Troy Cox
| Published: Dec 31, 2013
The Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes,…
Y ChromosomeTestisEmbryosChromosomesSex Chromosomes
“A Sex Chromosome Anomaly in a Case of Gonadal Dysgenesis (Turner’s Syndrome)” (1959), by Charles Edmund Ford, K. W Jones, Paul E. Polani, J. C De Almeida, and J. H Briggs
By: Megha Pillai
| Published: Aug 06, 2024
In 1959, Charles Edmund Ford and colleagues published “A Sex Chromosome Anomaly in a Case of Gonadal Dysgenesis (Turner’s Syndrome),” hereafter “A…
Turner SyndromeGonadal DysgenesisGonadal Dysgenesis, XOGonadal Dysgenesis, 45, XAbnormalities, Sex Chromosome