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Retinoids As Teratogens
By: Chanapa Tantibanchachai
| Published: Feb 28, 2014
Vitamin A (retinol) is an essential vitamin in the daily functioning of human beings that helps regulate cellular differentiation of epithelial…
RetinoidsVitamin A in the bodyTeratogenicity testingAbnormalities, HumanTeratogenic agents
Studies of Thalidomide's Effects on Rodent Embryos from 1962-2008
By: Joanna Yang, Chanapa Tantibanchachai
| Published: Mar 07, 2014
Thalidomide is a sedative drug introduced to European markets on 1 October 1957 after extensive testing on rodent embryos to ensure its safety. Early…
ContextTeratogenicity testingAbnormalities, HumanThalidomide--Side effectsThalidomide
Teratogens
By: Chanapa Tantibanchachai
| Published: Jan 22, 2014
Teratogens are substances that may produce physical or functional defects in the human embryo or fetus after the pregnant woman is exposed to the…
Abnormalities, HumanFetusPregnancyTeratogenicity testingEmbryos
"Experimental Studies on Congenital Malformations" (1959), by James G. Wilson
By: Chanapa Tantibanchachai
| Published: Jun 15, 2017
The article Experimental Studies on Congenital Malformations was published in the Journal of Chronic Diseases in 1959. The author, James G. Wilson,…
LiteratureAbnormalities, HumanBirth DefectsTeratologymalformations
Cocaine as a Teratogen
By: Mark Zhang, Chanapa Tantibanchachai
| Published: Oct 17, 2013
Cocaine use by pregnant women has a variety of effects on the embryo and fetus, ranging from various gastro-intestinal and cardiac defects to tissue…
CocaineCocaine abusePregnancyEmbryosFetus
Josef Warkany (1902–1992)
By: Chanapa Tantibanchachai, Bianca Zietal
| Published: May 26, 2017
Josef Warkany studied the environmental causes of birth defects in the United States in the twentieth century. Warkany was one of the first…
Abnormalities, HumanVitamin ARetinoidsHypervitaminosiscalomel
Sidney Q. Cohlan (1915-1999)
By: Bianca Zietal, Chanapa Tantibanchachai
| Published: Jun 18, 2017
Sidney Q. Cohlan studied birth defects in the US during the twentieth century. Cohlan helped to discover that if a pregnant woman ate too much…
Abnormalities, HumanRetinoidsVitamin AHypervitaminosisTetracycline
Isotretinoin (Accutane) as a Teratogen
By: Chanapa Tantibanchachai
| Published: Jul 20, 2014
Isotretinoin is a molecule and a byproduct (metabolite) of vitamin A, and in greater than normal amounts in pregnant women, it can cause fetal…
Teratogenic agentsVitamin AIsotretinoinAbnormalities, HumanTeratogens
US Regulatory Response to Thalidomide (1950-2000)
By: Chanapa Tantibanchachai
| Published: Apr 01, 2014
Thalidomide, a drug capable of causing fetal abnormalities (teratogen), has caused greater than ten thousand birth defects worldwide since its…
ContextThalidomideThalidomide--Side effectsTeratogenicity testingMultiple Myeloma
Thesis: From Monsters to Medicine: A Historical Analysis of Changes in the Field of Teratology Over the Twentieth Century
By: Chanapa Tantibanchachai
| Published: Jul 25, 2021
This project focuses on the history of how teratogens, or agents which have the potential to cause birth defects, have been understood and tested for…
Teratogenicity testingHistory, 20th CenturyHistory, Twentieth Century