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David Phillip Vetter was born with X-linked severe combined immunodeficiency disorder, or X-SCID, and spent most of his life in an isolated sterile…
X-Linked Combined Immunodeficiency DiseasesX-Linked SCIDSevere Combined ImmunodeficiencyBone Marrow--TransplantationAutoimmune DiseasesExperiments conducted by Elizabeth Blackburn, Carol Greider, and Jack Szostak from 1982 to 1989 provided theories of how the ends of chromosomes,…
TelomereGreider, Carol W.Chromosome replicationTelomeraseDNAThe Hayflick Limit is a concept that helps to explain the mechanisms behind cellular aging. The concept states that a normal human cell can only…
CellsCell populationsCell DeathApoptosisCell ProliferationLap-Chee Tsui is a geneticist who discovered the cystic fibrosis (CF) gene, and his research team sequenced human chromosome 7. As the location of…
PeopleTsui, Lap-CheeCystic FibrosisReproductionBiographyIn June 2015, the Ethics Committee of the American Society for Reproductive Medicine, or ASRM, published “Use of reproductive technology for sex…
LiteratureSex PreselectionFertilization in VitroReproductive technologyHuman reproductive technologyThe extraembryonic membranes that surround and originate from the embryos of vertebrates such as birds, reptiles, and mammals are crucial to their…
AmniocentesisReproductionFetusAmong other functions, the Notch signaling pathway forestalls the process of myogenesis in animals. The Notch signaling pathway is a pathway in…
MyogenesisNotch genesNotch ProteinsMusclesMyoblastsOn 1 February 1998, David T. Helm, Sara Miranda, and Naomi Angoff Chedd published “Prenatal Diagnosis of Down Syndrome: Mothers’ Reflections on…
Down syndromeCongenital AbnormalitiesGenetic disorders in pregnancygenetic testingAmniocentesisIn the second half of the twentieth century, scientists learned how to clone organisms in some species of mammals. Scientists have applied somatic…
CloningCell nuclei--TransplantationSpemann, Hans, 1869-1941Genetic EngineeringIn 2004, a team of researchers at Tufts-New England Medical Center in Boston, Massachusetts, investigated the fetal cells that remained in the…
CellsStem CellsMaternal-Fetal ExchangeFetal cells from maternal bloodFetus