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Edward B. Lewis studied embryonic development in Drosophila, including the discovery of the cis-trans test for recessive genes, and the…
PeopleDrosophilaBiographyIn "Selective Growth Stimulating Effects of Mouse Sarcoma on the Sensory and Sympathetic Nervous System of the Chick Embryo," Rita Levi-Montalcini…
Chick EmbryoExperimentsChicksMiceIn 1881 British opthalmologist Warren Tay made an unusual observation. He reported a cherry-red spot on the retina of a one-year-old patient, a…
Tay-Sachs DiseaseCongenital DisordersHeredityMichael D. West is a biomedical entrepreneur and investigator whose aim has been to extend human longevity with biomedical interventions. His focus…
PeopleStem CellsBiographyRegenerationIn 1964, authors James Till, Ernest McCulloch, and Louis Siminovitch, published A Stochastic Model of Stem Cell Proliferation, Based on The Growth of…
Stem CellsPluripotent Stem CellsAdult Stem CellsEmbryonic Stem CellsHematopoietic Stem CellsIn 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsFriedrich Leopold August Weismann published Das Keimplasma: eine Theorie der Vererbung (The Germ-Plasm: a Theory of Heredity, hereafter The Germ-…
LiteratureWeismann, August, 1834-1914. Keimplasma. EnglishGerm CellsHeredityInheritance of acquired charactersIsotretinoin is a molecule and a byproduct (metabolite) of vitamin A, and in greater than normal amounts in pregnant women, it can cause fetal…
Teratogenic agentsVitamin AIsotretinoinAbnormalities, HumanTeratogensThe DTaP vaccination series is an FDA-approved, five-shot vaccine for young children in the United States for protection against diphtheria, tetanus…
Diphtheria ToxoidDiphtheria ToxinCorynebacterium diphtheriaeDiphtheria-Tetanus VaccineDiphtheria-Tetanus-acellular Pertussis VaccinesIn 2015, biologist Helena D. Zomer and colleagues published the review article “Mesenchymal and Induced Pluripotent Stem Cells: General Insights and…
LiteratureStem CellsEmbryonic Stem CellsStem Cell ResearchIps