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Johannes Holtfreter (1901-1992)
By: Adam R. Navis
| Published: Feb 29, 2008
Johannes Holtfreter made important discoveries about the properties of the organizer discovered by Hans Spemann. Although he spent much time away…
Organizers, EmbryonicBiographyFrogs
George Herbert Hitchings (1905–1998)
By: Eboni E. Andersun
| Published: Jun 25, 2024
George Herbert Hitchings researched and developed medications that targeted specific parts of DNA replication processes to treat cancers and various…
Nucleoside analogDNA ReplicationDrug DevelopmentAcyclovirPharmacology
Association for Molecular Pathology v. Myriad Genetics, Inc. (2013)
By: Abigail Cave
| Published: Aug 02, 2024
In the 2013 legal case Association for Molecular Pathology v. Myriad Genetics, Inc., hereafter AMP v. Myriad, the United States Supreme Court held in…
PatentNucleotide sequenceBreast CancerBRCA1 geneBRCA2 gene
"On the Nature of the Process of Fertilization and the Artificial Production of Normal Larvae (Plutei) From the Unfertilized Eggs of the Sea Urchin" (1899), by Jacques Loeb
By: Steve Elliott
| Published: Jun 10, 2010
Jacques Loeb developed procedures to make embryos from unfertilized sea urchin eggs in 1899. Loeb called the procedures "artificial parthenogenesis…
ParthenogenesisExperimentsSea Urchins
Nerve Growth Factor
By: Adam R. Navis
| Published: Oct 30, 2007
Nerve growth factor (NGF) is a signaling protein and growth factor implicated in a wide range of development and maintenance functions. NGF was…
Nerve Growth FactorChicks
In the Womb: Identical Twins (2009), by National Geographic
By: Maggie Pingolt
| Published: Mar 08, 2012
National Geographic's documentary In the Womb: Identical Twins focuses on the prenatal development of human identical twins. Director Lorne Townend…
LiteratureTwinsDocumentary filmsTestosteroneMethylation
Wilhelm Roux (1850-1924)
By: Megan Kearl
| Published: Jul 22, 2009
Wilhelm Roux was a nineteenth-century experimental embryologist who was best known for pioneering Entwicklungsmechanik, or developmental mechanics.…
PeopleRoux, Wilhelm, 1850-1924Biography
Shoukhrat Mitalipov and Masahito Tachibana’s Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells (2009)
By: Giselle Lee
| Published: Jan 10, 2018
Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial Diseases
Essay: The Cuvier-Geoffroy Debate
By: Valerie Racine
| Published: Oct 07, 2013
In 1830, a dispute erupted in the halls of lÕAcad mie des Sciences in Paris between the two most prominent anatomists of the nineteenth century.…
EssayAnimals--ClassificationCuvier, Georges, baron, 1769-1832AnatomyBiological Evolution
Intraspecies Chimeras Produced in Laboratory Settings (1960-1975)
By: Sarah Taddeo
| Published: Nov 25, 2014
When cells-but not DNA-from two or more genetically distinct individuals combine to form a new individual, the result is called a chimera. Though…
ContextChimerismEmbryosEmbryonic Stem CellsMosaicism