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Shoukhrat Mitalipov and Masahito Tachibana’s Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells (2009)
By: Giselle Lee
| Published: Jan 10, 2018
Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial Diseases
The First Successful Cloning of a Gaur (2000), by Advanced Cell Technology
By: Caroline Appleton
| Published: Jul 26, 2013
Advanced Cell Technology (ACT), a stem cell biotechnology company in Worcester, Massachusetts, showed the potential for cloning to contribute to…
Cell nuclei--TransplantationCloningGaurAdvanced Cell Technology (Firm)Embryos
Elizabeth Blackburn, Carol Greider and Jack Szostak's Telomere and Telomerase Experiments (1982-1989)
By: Zane Bartlett
| Published: Mar 24, 2015
Experiments conducted by Elizabeth Blackburn, Carol Greider, and Jack Szostak from 1982 to 1989 provided theories of how the ends of chromosomes,…
TelomereGreider, Carol W.Chromosome replicationTelomeraseDNA
"Transfer of Fetal Cells with Multilineage Potential to Maternal Tissue" (2004), by Kiarash Khosrotehrani et al.
By: Alexis Abboud
| Published: Nov 14, 2014
In 2004, a team of researchers at Tufts-New England Medical Center in Boston, Massachusetts, investigated the fetal cells that remained in the…
CellsStem CellsMaternal-Fetal ExchangeFetal cells from maternal bloodFetus
"Presence of Fetal DNA in Maternal Plasma and Serum" (1997), by Dennis Lo, et al.
By: Cassidy Possehl
| Published: Mar 07, 2017
In the late 1990s researchers Yuk Ming Dennis Lo and his colleagues isolated fetal DNA extracted from pregnant woman’s blood. The technique enabled…
AmniocentesisChorionic Villus SamplingFetusObstetricsDNA
Amphioxus, and the Mosaic Theory of Development (1893), by Edmund Beecher Wilson
By: James Lowe
| Published: Mar 31, 2015
Edmund Beecher Wilson experimented with Amphioxus (Branchiostoma) embryos in 1892 to identify what caused their cells to differentiate into new types…
Wilson, Edmund B. (Edmund Beecher), 1856-1939AmphioxusEmbryosEmbryologyDevelopmental Biology
Temperature-Dependent Sex Determination in Reptiles
By: Karla T. Moeller
| Published: Feb 01, 2013
The sex of a reptile embryo partly results from the production of sex hormones during development, and one process to produce those hormones depends…
Sex DifferentiationReproductionAdaptationfetal developmentEmbryology
Experimental Studies on Germinal Localization (1904), by Edmund B. Wilson
By: James Lowe
| Published: Dec 22, 2014
At the turn of the twentieth century, Edmund B. Wilson performed experiments to show where germinal matter was located in molluscs. At Columbia…
Wilson, Edmund B. (Edmund Beecher), 1856-1939EmbryosEmbryologyDevelopmental BiologyLarvae
"Sheep Cloned by Nuclear Transfer from a Cultured Cell Line" (1996), by Keith Campbell, Jim McWhir, William Ritchie, and Ian Wilmut
By: Zane Bartlett
| Published: Sep 19, 2014
In 1995 and 1996, researchers at the Roslin Institute in Edinburgh, Scotland, cloned mammals for the first time. Keith Campbell, Jim McWhir, William…
CloningClone CellsCloning, MolecularCloning, OrganismExperiments
"Developmental Capacity of Nuclei Transplanted from Keratinized Skin Cells of Adult Frogs" (1975), by John Gurdon, Ronald Laskey, and O. Raymond Reeves
By: Sean Cohmer
| Published: Jun 14, 2011
In 1975 John Gurdon, Ronald Laskey, and O. Raymond Reeves published "Developmental Capacity of Nuclei Transplanted from Keratinized Skin Cells of…
Nuclear Transfer TechniquesExperimentsPublicationsFrogsNuclear Transplantation