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Edgar Allen and Edward A. Doisy's Extraction of Estrogen from Ovarian Follicles, (1923)
By: Brendan Van Iten
| Published: Mar 02, 2017
In the early 1920s, researchers Edgar Allen and Edward Adelbert Doisy conducted an experiment that demonstrated that ovarian follicles, which produce…
OvariesCorpus LuteumEndometriumEstrogenHormones, Sex
Hormone Replacement Therapy for Menopausal Symptoms
By: Megha Pillai
| Published: Jun 27, 2024
Hormone replacement therapy, or HRT, is a form of medication often used to treat the symptoms of menopause. According to the National Institute on…
MenopauseEstrogen Replacement TherapyEstrogen Progestin Combination TherapyMenopause--Hormone TherapyMenopause--Hormone Therapy--Complications
Clinical Tests of Estrogen Injections on Women with Abnormal Menstrual Cycles During the Early 1920s by Jean Paul Pratt and Edgar Allen
By: Brendan Van Iten
| Published: Apr 06, 2017
In the early twentieth century US, Jean Paul Pratt and Edgar Allen conducted clinical experiments on women who had abnormal menstrual cycles. During…
EstrogenEndocrinologyDoisy, Edward Adelbert, 1893-1986MenstruationUterus
Estrogen and the Menstrual Cycle in Humans
By: Brendan Van Iten
| Published: Jun 22, 2016
Estrogen is the primary sex hormone in women and it functions during the reproductive menstrual cycle. Women have three major types of estrogen:…
Menstrual CycleOral contraceptivesEstrogenEstradiolEstrone
The Effects of Diethylstilbestrol on Embryonic Development
By: Tristan Cooper-Roth
| Published: Sep 12, 2010
Estrogen plays a key role in the regulation of gene transcription. This is accomplished by its ability to act as a ligand and to bind to specific…
DiethylstilbestrolEstrogenHuman Development
Edgar Allen (1892–1943)
By: Brendan Van Iten
| Published: Jul 23, 2017
Edgar Allen identified and outlined the role of female sex hormones and discovered estrogen in the early 1900s in the US. In 1923, Allen, through his…
EstrogenHormones, SexOogenesisEstrusMenstrual Cycle
Diethylstilbestrol (DES) in the US
By: Alexis Abboud
| Published: Mar 23, 2015
Diethylstilbestrol (DES) is an artificially created hormone first synthesized in the late 1930s. Doctors widely prescribed DES first to pregnant…
DiethylstilbestrolDiethylstilbestrol--Side effectsDiethylstilbestrol--CarcinogenicityPregnancyEstrogen
"Adenocarcinoma of the Vagina: Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women" (1971), by Arthur L. Herbst, et al.
By: Alexis Abboud
| Published: Apr 12, 2017
Published in 1971, Adenocarcinoma of the Vagina: Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women, by Arthurs L.…
LiteratureDiethylstilbestrolAdenocarcinomaCancerEstrogen
"Experimental Studies on Congenital Malformations" (1959), by James G. Wilson
By: Chanapa Tantibanchachai
| Published: Jun 15, 2017
The article Experimental Studies on Congenital Malformations was published in the Journal of Chronic Diseases in 1959. The author, James G. Wilson,…
LiteratureAbnormalities, HumanBirth DefectsTeratologymalformations
Sindell v. Abbott Laboratories (1980)
By: Alexis Abboud
| Published: Jun 08, 2017
Sindell v. Abbott Laboratories was a 1980 California case that established the doctrine of market share liability for personal injury cases. For such…
LawDiethylstilbestrolMiscarriagePregnancy--ComplicationsPregnancy