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“A Sex Chromosome Anomaly in a Case of Gonadal Dysgenesis (Turner’s Syndrome)” (1959), by Charles Edmund Ford, K. W Jones, Paul E. Polani, J. C De Almeida, and J. H Briggs
By: Megha Pillai
| Published: Aug 06, 2024
In 1959, Charles Edmund Ford and colleagues published “A Sex Chromosome Anomaly in a Case of Gonadal Dysgenesis (Turner’s Syndrome),” hereafter “A…
Turner SyndromeGonadal DysgenesisGonadal Dysgenesis, XOGonadal Dysgenesis, 45, XAbnormalities, Sex Chromosome
Using Digital PCR to Detect Fetal Chromosomal Aneuploidy in Maternal Blood (2007)
By: Meilin Zhu
| Published: Nov 08, 2017
In 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidy
The Y-Chromosome in Animals
By: Dorothy R. Haskett
| Published: May 28, 2015
The Y-chromosome is one of a pair of chromosomes that determine the genetic sex of individuals in mammals, some insects, and some plants. In the…
Y ChromosomeSex ChromosomesEmbryosDNAChromosomes
Sex-determining Region Y in Mammals
By: Troy Cox
| Published: Dec 31, 2013
The Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes,…
Y ChromosomeTestisEmbryosChromosomesSex Chromosomes
Carol Widney Greider (1961-)
By: Zane Bartlett
| Published: Jan 26, 2015
Carol Widney Greider studied telomeres and telomerase in the US at the turn of the twenty-first century. She worked primarily at the University of…
Greider, Carol W.Women Nobel Prize winnersNobel Prize winnersTelomeraseTelomere
Telomeres and Telomerase in Cellular Aging (Senescence)
By: Zane Bartlett
| Published: Feb 11, 2015
Telomeres are sequences of DNA on the ends of chromosomes that protect chromosomes from sticking to each other or tangling, which could cause…
TelomeraseGreider, Carol W.Wistar Institute of Anatomy and BiologyAgingDNA
Telomerase in Human Development
By: Zane Bartlett
| Published: Mar 23, 2015
Telomerase is an enzyme that regulates the lengths of telomeres in the cells of many organisms, and in humans it begins to function int the early…
TelomeraseTelomereDNAMolecular BiologySomatic embryogenesis
Elizabeth Blackburn, Carol Greider and Jack Szostak's Telomere and Telomerase Experiments (1982-1989)
By: Zane Bartlett
| Published: Mar 24, 2015
Experiments conducted by Elizabeth Blackburn, Carol Greider, and Jack Szostak from 1982 to 1989 provided theories of how the ends of chromosomes,…
TelomereGreider, Carol W.Chromosome replicationTelomeraseDNA
"Presence of Fetal DNA in Maternal Plasma and Serum" (1997), by Dennis Lo, et al.
By: Cassidy Possehl
| Published: Mar 07, 2017
In the late 1990s researchers Yuk Ming Dennis Lo and his colleagues isolated fetal DNA extracted from pregnant woman’s blood. The technique enabled…
AmniocentesisChorionic Villus SamplingFetusObstetricsDNA
Meselson, Stahl, and the Replication of DNA: A History of "The Most Beautiful Experiment in Biology" (2001), by Frederic Lawrence Holmes
By: Victoria Hernandez
| Published: Jul 23, 2017
In 2001, Yale University Press published Frederic Lawrence Holmes' book, Meselson, Stahl, and the Replication of DNA: A History of "The Most…
LiteratureWatson, James D., 1928-Crick, Francis, 1916-2004Marine Biological Laboratory (Woods Hole, Mass.)DNA Replication