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In 1980, Ernesto Ippolito and Ignacio Ponseti published their results on a histological study they performed on congenital club foot in human fetuses…
ClubfootPonseti, I. V. (Ignacio V.), 1914-2009Abnormalities, HumanHistologyHistology, PathologicalThe article Experimental Studies on Congenital Malformations was published in the Journal of Chronic Diseases in 1959. The author, James G. Wilson,…
LiteratureAbnormalities, HumanBirth DefectsTeratologymalformationsWilliam John Little was one of the first orthopedic surgeons to research congenital malformations and their causes in the nineteenth century and…
Birth injuries--ComplicationsCerebral PalsyCerebral palsiedMuscle SpasticitySpasticityJosef Warkany studied the environmental causes of birth defects in the United States in the twentieth century. Warkany was one of the first…
Abnormalities, HumanVitamin ARetinoidsHypervitaminosiscalomelTeratogens are substances that may produce physical or functional defects in the human embryo or fetus after the pregnant woman is exposed to the…
Abnormalities, HumanFetusPregnancyTeratogenicity testingEmbryosIn 1861, William John Little published, “On The Influence of Abnormal Parturition, Difficult Labors, Premature Birth, and Asphyxia Neonatorum, on the…
LiteratureBirth injuries--ComplicationsCerebral PalsyCerebral palsiedMuscle SpasticityThalidomide is a sedative drug introduced to European markets on 1 October 1957 after extensive testing on rodent embryos to ensure its safety. Early…
ContextTeratogenicity testingAbnormalities, HumanThalidomide--Side effectsThalidomideSidney Q. Cohlan studied birth defects in the US during the twentieth century. Cohlan helped to discover that if a pregnant woman ate too much…
Abnormalities, HumanRetinoidsVitamin AHypervitaminosisTetracyclineEnvironment and Birth Defects by James Graves Wilson in the US was published in 1973. The book summarized information on the causes of malformations…
LiteratureBirth DefectsAbnormalities, HumanTeratogensTeratologyThe concept Fetal Alcohol Syndrome (FAS) refers to a set of birth defects that occur in children born to mothers who abused alcohol during pregnancy…
fetal alcohol syndromeAbnormalities, HumanCentral Nervous SystemalcoholPregnancy