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Fortunio Liceti studied natural philosophy and medicine in Italy during the first half of the seventeenth century. Liceti wrote greater than seventy…
TeratologyAbnormalities, HumanAnimals--AbnormalitiesEmbryologyPathologyIsidore Geoffroy Saint-Hilaire studied anatomy and congenital abnormalities in humans and other animals in nineteenth century France. Under the…
TeratologyAnimals--AbnormalitiesAbnormalities, HumanNatural historyAnatomyTruman William Brophy developed a cleft palate surgical repair, later called the Brophy Operation, in the late nineteenth century US. The procedure…
Cleft PalateDental EducationAmerican Dental AssociationmalformationsBirth DefectsJames Graves Wilson's six principles of teratology, published in 1959, guide research on teratogenic agents and their effects on developing organisms…
TeratologyAbnormalities, HumanCongenital AbnormalitiesBirth DefectsCongenital DefectsVitamin A (retinol) is an essential vitamin in the daily functioning of human beings that helps regulate cellular differentiation of epithelial…
RetinoidsVitamin A in the bodyTeratogenicity testingAbnormalities, HumanTeratogenic agentsVirginia Apgar worked as an obstetrical anesthesiologist, administering drugs that reduce women’s pain during childbirth, in the US in the mid-…
Apgar, Virginia, 1909-1974Apgar ScorePregnancyObstetricsChildbirthIsotretinoin is a molecule and a byproduct (metabolite) of vitamin A, and in greater than normal amounts in pregnant women, it can cause fetal…
Teratogenic agentsVitamin AIsotretinoinAbnormalities, HumanTeratogensIn its 1993 decision Daubert v. Merrell Dow Pharmaceuticals, Inc., the US Supreme Court established the Daubert Standard for evaluating the…
LawBendectin (Trademark)Morning SicknessSedativesAbnormalities, Human