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A Series of YouTube Videos Detailing the “CRISPR Babies” Experiment (2018), by He Jiankui
By: Risa Aria Schnebly, Brianna Ellis
| Published: Jul 31, 2021
In 2018, He Jiankui uploaded a series of videos to a YouTube channel titled “The He Lab” that detailed one of the first instances of a successful…
Literaturegene editingGenome EditingCRISPR (Genetics)CRISPR-associated protein 9
“Survival of Mouse Embryos Frozen to -196 ° and -269 °C” (1972), by David Whittingham, Stanley Leibo, and Peter Mazur
By: Risa Aria Schnebly
| Published: Oct 01, 2020
In 1972, David Whittingham, Stanley Leibo, and Peter Mazur published the paper, “Survival of Mouse Embryos Frozen to -196 ° and -269 °C,” hereafter…
LiteratureCultures (Biology)--CryopreservationCells--CryopreservationMolecular weightsCryobiology
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
Embryonic Sex Differentiation and Sex Hormones (1947), by Carl R. Moore
By: Mary Drago
| Published: May 03, 2014
In 1947, Carl Richard Moore, a researcher at the University of Chicago, in Chicago, Illinois, wrote Embryonic Sex Differentiation and Sex Hormones,…
LiteratureEndocrinologyHormones, SexGonadal Steroid HormonesFreemartinism
"The Development of the Turtle Carapace" (1989), by Ann Campbell Burke
By: Guido Caniglia
| Published: Oct 20, 2011
Ann Campbell Burke examines the development and evolution of vertebrates, in particular, turtles. Her Harvard University experiments, described in…
LiteratureExperimentsPublicationsTurtlesEvolution
"Programmed Cell Death-II. Endocrine Potentiation of the Breakdown of the Intersegmental Muscles of Silkmoths" (1964), by Richard A. Lockshin and Carroll M. Williams
By: Lijing Jiang
| Published: Apr 27, 2011
Richard A. Lockshin's 1963 PhD dissertation on cell death in insect metamorphosis was conducted under the supervision of Harvard insect physiologist…
LiteratureExperimentsPublicationsSilkwormsHormones
"The Effects of Wing Bud Extirpation on the Development of the Central Nervous System in Chick Embryos" (1934), by Viktor Hamburger
By: Lijing Jiang
| Published: Nov 22, 2010
German embryologist Viktor Hamburger came to the US in 1932 with a fellowship provided by the Rockefeller Foundation. Hamburger started his research…
LiteraturePublicationsExperimentsNervous SystemChicks
"Generation of Induced Pluripotent Stem Cells without Myc from Mouse and Human Fibroblasts" (2007), by Masato Nakagawa et al.
By: Samuel Philbrick
| Published: Nov 20, 2010
In November 2007, Masato Nakagawa, along with a number of other researchers including Kazutoshi Takahashi, Keisuke Okita, and Shinya Yamanaka,…
LiteratureStem CellsPublicationsExperimentsMice
"Contributions to the Development of the Embryo. On the Artificial Production of One of the First Two Blastomeres, and the Later Development (Postgeneration) of the Missing Half of the Body" (1888), by Wilhelm Roux
By: Megan Kearl
| Published: Jul 20, 2009
Wilhelm Roux was an influential figure in the early history of experimental embryology. Although he originally studied medicine, he was invited to be…
LiteratureRoux, Wilhelm, 1850-1924ExperimentsFrogsOva