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Edward Charles Dodds researched the function and effects of natural and artificial hormones on the endocrine system in England during the twentieth…
Dodds, E. C. (Edward Charles), 1899-EndocrinologyEstrogenDiethylstilbestrolDiethylstilbestrol--CarcinogenicityThe hedgehog signaling pathway is a mechanism that regulates cell growth and differentiation during embryonic development, called embryogenesis, in…
Drosophila melanogasterCyclopiaGenetic regulationZebra danioGenesDiethylstilbestrol (DES) is an artificially created hormone first synthesized in the late 1930s. Doctors widely prescribed DES first to pregnant…
DiethylstilbestrolDiethylstilbestrol--Side effectsDiethylstilbestrol--CarcinogenicityPregnancyEstrogenCold Spring Harbor Laboratory (CSHL) is a non-profit research institution that specializes in cancer, neuroscience, plant biology, quantitative…
OrganizationWatson, James D., 1928-EugenicsBacteriophagesBrenner, SydneyLeo Loeb developed an experimental approach to studying cancer and pioneered techniques for tissue culture and in vitro tissue transplantation which…
PeopleMarine Biological Laboratory (Woods Hole, Mass.)Embryology, ExperimentalTissue cultureEmbryosThomas Joseph King Jr. was a developmental biologist who, with fellow scientist Robert Briggs, pioneered a method of transplanting nuclei from…
PeopleNuclear Transfer TechniquesBiographyNuclear TransplantationCancer"Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics" (hereafter abbreviated as "Apoptosis") was published in…
LiteratureApoptosisPublicationsCancerCell DeathThe p53 protein acts as a pivotal suppressor of inappropriate cell proliferation. By initiating suppressive effects through induction of apoptosis,…
Tumor Suppressor Protein p53ExperimentsCancerCell DeathThe discovery of hematopoietic stem cells (HSCs) provided a pioneering step in stem cell research. HSCs are a type of multipotent adult stem cell,…
Hematopoietic Stem CellsStem CellsmedicineCancer