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George Herbert Hitchings (1905–1998)
By: Eboni E. Andersun
| Published: Jun 25, 2024
George Herbert Hitchings researched and developed medications that targeted specific parts of DNA replication processes to treat cancers and various…
Nucleoside analogDNA ReplicationDrug DevelopmentAcyclovirPharmacology
“Genetical Implications of the Structure of Deoxyribonucleic Acid” (1953), by James Watson and Francis Crick
By: Victoria Hernandez
| Published: Jan 13, 2020
In May 1953, scientists James Watson and Francis Crick wrote the article “Genetical Implications of the Structure of Deoxyribonucleic Acid,”…
LiteratureDNANucleic AcidsDeoxyriboseGenetics
“Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid” (1953), by James Watson and Francis Crick
By: Victoria Hernandez
| Published: Oct 31, 2019
In April 1953, James Watson and Francis Crick published “Molecular Structure of Nucleic Acids: A Structure of Deoxyribose Nucleic Acid” or “A…
LiteratureDNAComplementary DNADNA ReplicationDeoxyribonucleic Acid
Categorization of Conservative, Semi-Conservative, and Dispersive DNA Replication Theories (1953–1956)
By: Victoria Hernandez
| Published: Oct 31, 2019
In 1956, Gunther Stent, a scientist at the University of California Berkeley in Berkeley, California, coined the terms conservative, semi-…
DNADNA ReplicationDNA HelicasesGenesHeredity
The Debate over DNA Replication Before the Meselson-Stahl Experiment (1953–1957)
By: Victoria Hernandez
| Published: Jan 03, 2018
Between 1953 and 1957, before the Meselson-Stahl experiment verified semi-conservative replication of DNA, scientists debated how DNA replicated. In…
ChromosomesCalifornia Institute of TechnologyCold Spring Harbor LaboratoryDNA Replication
Equilibrium Density Gradient Centrifugation in Cesium Chloride Solutions Developed by Matthew Meselson and Franklin Stahl
By: Victoria Hernandez
| Published: Dec 19, 2017
Matthew Meselson, Franklin Stahl, and Jerome Vinograd, developed cesium chloride, or CsCl, density gradient centrifugation in the 1950s at the…
TechnologyDNA ReplicationDNA replication--RegulationCentrifugation, Density GradientOrganonitrogen compounds
"On the Replication of Desoxyribonucleic Acid (DNA)" (1954), by Max Delbruck
By: Victoria Hernandez
| Published: Sep 21, 2017
In 1954 Max Delbruck published On the Replication of Desoxyribonucleic Acid (DNA) to question the semi-conservative DNA replication mechanism…
LiteratureHolmes, Frederic LawrenceMeselson, MatthewStahl, Franklin W.Watson, James D., 1928-
Max Ludwig Henning Delbruck (1906–1981)
By: Victoria Hernandez
| Published: Sep 20, 2017
Max Ludwig Henning Delbrick applied his knowledge of theoretical physics to biological systems such as bacterial viruses called bacteriophages, or…
Meselson, MatthewUniversity of RochesterDNA ReplicationBacteriophagesEscherichia coli
Meselson, Stahl, and the Replication of DNA: A History of "The Most Beautiful Experiment in Biology" (2001), by Frederic Lawrence Holmes
By: Victoria Hernandez
| Published: Jul 23, 2017
In 2001, Yale University Press published Frederic Lawrence Holmes' book, Meselson, Stahl, and the Replication of DNA: A History of "The Most…
LiteratureWatson, James D., 1928-Crick, Francis, 1916-2004Marine Biological Laboratory (Woods Hole, Mass.)DNA Replication
Franklin William Stahl (1929– )
By: Victoria Hernandez
| Published: Jul 20, 2017
Franklin William Stahl studied DNA replication, bacteriophages, and genetic recombination in the US during the mid-twentieth and early twenty-first…
DNA SequenceNucleotide sequenceDNA ReplicationDNA--SynthesisDNA replication--Regulation