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Elizabeth Blackburn, Carol Greider and Jack Szostak's Telomere and Telomerase Experiments (1982-1989)
By: Zane Bartlett
| Published: Mar 24, 2015
Experiments conducted by Elizabeth Blackburn, Carol Greider, and Jack Szostak from 1982 to 1989 provided theories of how the ends of chromosomes,…
TelomereGreider, Carol W.Chromosome replicationTelomeraseDNA
Telomeres and Telomerase in Cellular Aging (Senescence)
By: Zane Bartlett
| Published: Feb 11, 2015
Telomeres are sequences of DNA on the ends of chromosomes that protect chromosomes from sticking to each other or tangling, which could cause…
TelomeraseGreider, Carol W.Wistar Institute of Anatomy and BiologyAgingDNA
Paternal Sperm Telomere Elongation and Its Impact on Offspring Fitness
By: Joanna Yang, Zane Bartlett
| Published: Feb 07, 2017
Telomeres are structures at the ends of DNA strands that get longer in the DNA of sperm cells as males age. That phenomenon is different for most…
TelomereAgingSpermSpermatozoaTelomerase
Telomerase in Human Development
By: Zane Bartlett
| Published: Mar 23, 2015
Telomerase is an enzyme that regulates the lengths of telomeres in the cells of many organisms, and in humans it begins to function int the early…
TelomeraseTelomereDNAMolecular BiologySomatic embryogenesis
"Sheep Cloned by Nuclear Transfer from a Cultured Cell Line" (1996), by Keith Campbell, Jim McWhir, William Ritchie, and Ian Wilmut
By: Zane Bartlett
| Published: Sep 19, 2014
In 1995 and 1996, researchers at the Roslin Institute in Edinburgh, Scotland, cloned mammals for the first time. Keith Campbell, Jim McWhir, William…
CloningClone CellsCloning, MolecularCloning, OrganismExperiments
"Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts" (1997), by Angelika E. Schnieke, et al.
By: Zane Bartlett
| Published: Aug 19, 2014
In the 1990s, researchers working at the Roslin Institute in Edinburgh, Scotland, performed cloning experiments in collaboration with PPL…
CloningChristmas FactorBlood coagulation factor IXRoslin InstituteWilmut, Ian
The Hayflick Limit
By: Zane Bartlett
| Published: Nov 14, 2014
The Hayflick Limit is a concept that helps to explain the mechanisms behind cellular aging. The concept states that a normal human cell can only…
CellsCell populationsCell DeathApoptosisCell Proliferation
Induced Pluripotent Stem Cell Experiments by Kazutoshi Takahashi and Shinya Yamanaka in 2006 and 2007
By: Zane Bartlett
| Published: Jun 01, 2015
In 2006, Kazutoshi Takahashi and Shinya Yamanaka reprogrammed mice fibroblast cells, which can produce only other fibroblast cells, to become…
Stem cells--ResearchStem CellsNobel PrizesEmbryologyDevelopmental Biology
Carol Widney Greider (1961-)
By: Zane Bartlett
| Published: Jan 26, 2015
Carol Widney Greider studied telomeres and telomerase in the US at the turn of the twenty-first century. She worked primarily at the University of…
Greider, Carol W.Women Nobel Prize winnersNobel Prize winnersTelomeraseTelomere
"Viable Offspring Derived from Fetal and Adult Mammalian Cells" (1997), by Ian Wilmut et al.
By: Zane Bartlett
| Published: Oct 10, 2014
In the 1990s, Ian Wilmut, Jim McWhir, and Keith Campbell performed experiments while working at the Roslin Institute in Roslin, Scotland. Wilmut,…
CloningMolecular CloningClone CellsCampbell, Keith, 1954-2012Roslin Institute