Jane Marion Oppenheimer, embryologist and historian of science and medicine, was born on 19 September 1911 in Philadelphia, Pennsylvania, to Sylvia Stern and James H. Oppenheimer. After studying zoology at Bryn Mawr College, Oppenheimer received her AB degree in 1932. Oppenheimer received her PhD in embryology at Yale University in 1935 and worked as a research fellow from 1935-1936. While at Yale she was influenced by the work of Ross Granville Harrison and John Spangler Nicholas, the latter of whom was Oppenheimer's PhD advisor. While working with Nicholas, she studied the embryology of killifish (Fundulus hereoclitus) using Nicholas s method for dechorionating the embryo, which made it possible to perform precise experimental manipulations on teleost embryos. Oppenheimer became interested in teleosts after studying the history of biology as a graduate student and published a part of her dissertation, "Historical Introduction to the Study of Teleostean Development," in the History of Science Society journal Osiris. From 1934-1937 she published numerous noteworthy papers discussing Fundulus embryology. Oppenheimer performed fate mapping experiments and developed a staging series for Fundulus embryos. When the United States and the USSR developed Apollo-Soyuz as a joint space venture, Oppenheimer used Fundulus embryos to design an experiment that tested the effects of a zero-gravity environment on embryonic development.

Wilhelm His, Sr. was born on 9 July 1831 in Basel, Switzerland, to Katharina La Roche and Eduard His. He began his medical studies at Basel in 1849 and later transferred to the University of Bern during the winter semester of 1849-1850. A year later, His arrived at the University of Berlin, where he studied under Johannes Müller and Robert Remak. For his clinical training, His attended the University of Würzburg from 1852-1853. During his training, however, His became more interested in the theoretical teachings of Rudolf Virchow, Albert von Kölliker, and Franz von Leydig than in clinical instruction. While at Würzburg, His also studied the writings of Carl Ludwig and Hermann Lotze, and he concluded his schooling with visits to Prague and Vienna, where he met Ernst von Brucke and Karl Rokitansky.

A pioneer in experimental embryology, Ross Granville Harrison made numerous discoveries that advanced biology. One of the most significant was his adaptation of the hanging drop method from bacteriology to carry out the first tissue culture. This method allowed for further studies in embryology as well as experimental improvements in oncology, virology, genetics, and a number of other fields. Prior to Harrison's innovation, a number of scientists, including Julius Arnold, Gustav Born, Leo Loeb, and Gottlieb Haberlandt, had attempted to grow tissues in isolation in vitro and in vivo but with much less success than Harrison. In addition, Harrison contributed to the understanding of organization and differentiation.

As the third director of the Carnegie Institute of Washington s Department of Embryology, George Washington Corner made a number of contributions to the life sciences as well as to administration. Corner was born on 12 December 1889 in Baltimore, Maryland, near the newly established Johns Hopkins University. Although Corner was not exposed to science much in school at a young age, he developed an early appreciation for science through conversations with his father about geography and by looking through the family's National Geographic magazines.

Subscribe to Kimberly A. Buettner