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Richard A. Lockshin's 1963 PhD dissertation on cell death in insect metamorphosis was conducted under the supervision of Harvard insect physiologist…
LiteratureExperimentsPublicationsSilkwormsHormonesThe sex of a reptile embryo partly results from the production of sex hormones during development, and one process to produce those hormones depends…
Sex DifferentiationReproductionAdaptationfetal developmentEmbryologyBisphenol A (BPA) is an organic compound that was first synthesized by Aleksandr Dianin, a Russian chemist from St. Petersburg, in 1891. The chemical…
bisphenol AReproductionHormonesHuman DevelopmentIn his 1991 article Screening for Congenital Hypothyroidism, Delbert A. Fisher in the US reported on the implementation and impact of mass neonatal…
LiteratureCongenital HypothyroidismNewborn infants--DevelopmentCretinismInfant Health ServicesIn 1996, the US Congress mandated that the US Environmental Protection Agency (EPA) create and regulate the Endocrine Disruptor Screening Program.…
Endocrine disrupting chemicalsEndocrine toxicologyDevelopmental endocrinologyEndocrine SystemHormonesDiethylstilbestrol (DES) is an artificially created hormone first synthesized in the late 1930s. Doctors widely prescribed DES first to pregnant…
DiethylstilbestrolDiethylstilbestrol--Side effectsDiethylstilbestrol--CarcinogenicityPregnancyEstrogenEstrogen is the primary sex hormone in women and it functions during the reproductive menstrual cycle. Women have three major types of estrogen:…
Menstrual CycleOral contraceptivesEstrogenEstradiolEstroneFrank Rattray Lillie's research on freemartins from 1914 to 1920 in the US led to the theory that hormones partly caused for sex differentiation in…
Lillie, Frank Rattray, 1870-1947Intersexuality in animalsFreemartinismHormonesExperimentsIn 1948, Olive Watkins Smith published 'Diethylstilbestrol in the Prevention and Treatment of Complications of Pregnancy' in the American Journal…
LiteraturePregnancyEndocrine disrupting chemicalsHormonesObstetricsSindell v. Abbott Laboratories was a 1980 California case that established the doctrine of market share liability for personal injury cases. For such…
LawDiethylstilbestrolMiscarriagePregnancy--ComplicationsPregnancy